CTOS
15th Annual Meeting
November 5–7, 2009
Miami, FL
Schedule: Thursday | Friday | Saturday
| Thursday, November 5, 2009 |
|
| 1:15 - 2:15 p.m. |
Session 1—Diagnostic Radiology Moderator: Doug Hawkins |
| 23 | #39422 APPLICATION OF THE LODWICK CLASSIFICATION TO ALL PRIMARY BONE NEOPLASMS M Stephen Wilson; G A Marulanda; H Thomas Temple; M J. Kransdorf; G Douglas Letson1 |
| 23 | #39423 RELIABILITY OF CHOI AND RECIST CRITERIA FOR ASSESSING TREATMENT RESPONSE IN SOFT TISSUE SARCOMAS P W. O'Donnell; J W. Froelich; T Dhurairaj; T E. DeFor; E Y. Cheng |
| 23 | #39412 PROSPECTIVE TRIAL CORRELATING FDG PET-CT WITH HISTOLOGIC RESPONSE AFTER NEOADJUVANT CHEMOTHERAPY FOR SOFT TISSUE SARCOMAS E Y. Cheng; J W. Froelich; J Carlos Manivel; B J. Weigel; P W. O'Donnell; K M. Skubitz |
| 24 | #39446 RADIOLOGY STUDY COMPROMISE FROM NON-STANDARDIZED VIEWING PLATFORMS - WHY WE HATE OUTSIDE CDS W Goode Ward; P Michael Lichstein; S Wilson |
| 2:15 - 3:30 p.m. |
Session 2—Biology Moderator: Torsten Nielsen, Akira Kawai |
| 24 | #39425 ROLE OF MICRORNAS IN UTERINE LEIOMYOSARCOMA M Linley Anderson; M F Khan; E Olokpa; H Zhu; N Ewelike; S Orsulic; R S Roden; D G Thomas; C R Creighton; P Gunaratne |
| 24 | #39311 COMPREHENSIVE MAPPING OF P53 PATHWAY MUTATIONS IN SARCOMAS D Thomas; S Young; D Garsed; P Choong; C Hemmings; I Dickinson; L Barys; M Ito; J Lisztwan; J Desai1 |
| 25 | #39229 DUAL TARGETING OF AKT AND MTOR: A POTENTIAL THERAPUETIC APPROACH FOR MALIGNANT PERIPHERAL NERVE SHEATH TUMOR D Katz; Z Changye; Q Zhu; J Liu; I E McCutcheon; J M Slopis; A Lazar; R E Pollock; D Lev |
| 25 | #39350 DRIVEN TO DEATH: INHIBITION OF FARNESYLATION COUNTERINTUITIVELY CAUSES INCREASED RAS ACTIVITY, RESULTING IN ERK AND P38 ACTIVATION AND DEATH IN SENSITIVE OSTEOSARCOMA CELLS M Geryk Hall; Y Yang; D Patrick Meehan Hughes |
| 25 | #38968 CORRELATION OF DECELERATED TUMOR GROWTH AND DIMINISHED C-MYC EXPRESSION FOLLOWING VEGF BLOCKADE TO A MURINE OSTEOSARCOMA D Yin; L Bai; W J Hendry; P H Wooley; S Yang |
| 26 | #39237 ANTIBODIES TARGETING CSF-1 IMPEDE MACROPHAGE RECRUITMENT IN A PIGMENTED VILLONODULAR SYNOVITIS RENAL SUBCAPSULAR IMPLANT MODEL H Cheng; D Gao; P W Clarkson; T O. Nielsen |
| 4:15 - 4:30 p.m. | Poster Discussion 1 –Surgical Oncology Moderator: Chandrajit Raut |
| 26 | #38664 PROGRESS IN THE TREATMENT OF OSTEOSARCOMA. A POPULATIONBASED STUDY OF 3089 PATIENTS DIAGNOSED OVER 33 YEARS A Mohammad Shehadeh; I Sultan; I Qaddoumi; C Rodriguez-Galindo |
| 26 | #38997 STANDARDIZED PHYSICAL THERAPY PROTOCOL FOLLOWING LIMB SALVAGE SURGERY FOR BONE TUMORS A Shehadeh; I Sultan; M Dahleh; R Henshaw |
| 27 | #39010 THE OUTCOME OF LIMB SALVAGE SURGERY AT A DEVELOPING COUNTRY CAN BE COMPARED TO THAT AT HIGH RANK CENTERS IN DEVELOPED COUNTRIES WHEN ENOUGH RESOURCES ARE AVAILABLE A Shehadeh; I Sultan; S Yaser |
| 27 | #39182 CONSEQUENCES OF UNPLANNED EXCISION OF SOFT TISSUE SARCOMA R L. Slotcavage; V. M. Moretti; R D. Lackman; C M. Ogilvie |
| 28 | #39190 IMPACT OF IMPROVED LIMB SPARING SURGERY ON ONCOLOGIC OUTCOME IN HIGH GRADE OSTEOSARCOMA G Luis Farfalli; L Alberto Aponte-Tinao; M Angel Ayerza; D Muscolo |
| 28 | #39196 OUTCOMES ASSOCIATED WITH FOREQUARTER, HINDQUARTER AMPUTATIONS AND INTERNAL HEMIPELVECTOMIES J Scott Zager; R J Gonzalez; S S Marzban; D Johnson; G Douglas Letson; D Cheong |
| 28 | #39202 OUTCOMES BASED ON PRIMARY TUMOR SIZE IN UTERINE LEIOMYOSARCOMA (LMS) GROSSLY CONFINED TO THE UTERINE CORPUS AND/ OR CERVIX M Mendes Leitao Jr; O Zivanovic; R A Soslow; M A Hensley; R R Barakat |
| 29 | #39204 CURRENT AJCC STAGING INADEQUATELY PREDICTS SURVIVAL AFTER RESECTION OF RETROPERITONEAL SARCOMA H Nathan1; C Raut2; K A Thornton1; J Herman1; R Schulick1; M Choti1; T Pawlik1 |
| 29 | #39214 ANALYSIS OF PROGNOSTIC FACTORS IN EPITHELIOID SARCOMA USING A POPULATION-BASED CANCER REGISTRY M Ly Nguyen; J Lee; A Ziogas; J Zell; B Hoang |
| 29 | #39219 INTRA-OPERATIVE NAVIGATION FOR MINIMALLY INVASIVE RESECTION OF PERIACETABULAR TUMORS R Randall; R A Ward; K B Jones |
| 29 | #39220 MULTI-CENTER INITIAL EXPERIENCE WITH COMPLIANT ACETABULAR FIXATION FOR MASSIVE PELVIC RESECTIONS R Randall; R Phelps; R A Ward; C Beauchamp; A Fang; J O Johnston; K B Jones; H T Kim; M W Manoso; J Healey |
| 30 | #39227 KYPHOPLASTY FOR FRAGILITY FRACTURES OF THE SPINE: THE NEED FOR INTRAOPERATIVE BIOPSY M S Wilson; G. D L; J M. Small; G Marulanda |
| 30 | #39232 COMPLETE SOFT TISSUE SARCOMA RESECTION IS A VIABLE TREATMENT OPTION FOR SELECT ELDERLY PATIENTS G Lahat; L Sharon; L Alexander; L Valera; P Lin; F Barry; J Cormier; K Hunt; P Pisters; R Pollock; D Lev |
| 30 | #39234 SPACE SARCOMAS: A PROPOSED SURGICAL CLASSIFICATION SYSTEM, AND A SYSTEMATIC APPROACH TO THE SURGICAL TREATMENT FOR SARCOMAS OF THE VARIOUS ANATOMIC SPACES : THE FEMORAL TRIANGLE, SARTORIAL CANAL AND POPLITEAL SPACE: ANALYSIS OF 53 CASES A Sternheim1; M Miles Malawer1; j Bickels1; T Ben-Tov1 |
| 31 | #39243 PRIMARY RECONSTRUCTIONS OF THE LOWER LIMB WITH MODULAR PROSTHESES: AN ANALYSIS OF IMPLANT SURVIVAL. # P Ruggieri; E Pala; C Novella Abati; T Calabrò; M Mercuri |
| 31 | #39244 OSTEOSARCOMA IN PAGET'S DISEASE OF BONE: A RETROSPECTIVE ANALYSIS OF THE RIZZOLI INSTITUTE EXPERIENCE. # P Ruggieri; T Calabrò; E Pala; G Ussia; M Mercuri |
| 32 | #39245 PROSTHETIC RECONSTRUCTION OF THE PROXIMAL HUMERUS AFTER RESECTION OF METASTASIS P Ruggieri; T Calabrò; E Pala; G Ussia; A Angelini; G Rossi; M Mercuri |
| 32 | #39256 MANAGEMENT OF RETROPERITONEAL SARCOMAS: SINGLE INSTITUTION EXPERIENCE. A Kaminski; J Strojek; B Pilecki; I Cedrych; Z Kolosza |
| 33 | #39258 A PHASE II STUDY OF SOFT TISSUE SARCOMA RESPONSE USING FDGPET TO DOXORUBICIN AND IFOSFAMIDE CHEMOTHERAPY IN PATIENTS WITH RESECTABLE DISEASE S M Schuetze; D S Hawkins; B P Rubin; E U Conrad III; J E Butrynski; E Rodler; J F Eary |
| 33 | #39259 EVALUATION OF THE ROLE OF THERMAL ABLATION IN THE TREATMENT OF SOFT TISSUE SARCOMAS R E O'Cearbhaill; R G Maki; J Zheng; A Iasonos; C Ariyan; S Solomon; M Hensley |
| 33 | #39272 HISTOLOGIC SUBTYPE PREDICTS SURVIVAL IN PATIENTS WITH RETROPERITONEAL SARCOMA W Tseng; S R Martinez; R M Tamurian; D Borys; R J Canter 34 #39293 A COMPARATIVE STUDY OF THE COMPLICATIONS AND FUNCTIONAL OUTCOMES OF ENDOPROSTHETIC REPLACEMENTS AND ROTATIONPLASTY IN CHILDHOOD. A Abudu; P El-Dalil; T Warrener; M de Souza; R Grimer |
| 34 | #39296 SURGICAL MANAGEMENT AND TREATMENT STRATEGY OF EXTRAABDOMINAL FIBROMATOSIS T Ben-Tov; T Pritsch; A Sternheim; J Bickels; M Miles Malawer |
| 34 | #39301 HMW-MAA AND B7-H3 AS PROGNOSTIC BIOMARKERS IN CHORDOMA A J Schoenfeld; F J Hornicek; D Springfi eld; H Mankin; S Ferrone; J H Schwab |
| 35 | #39329 WIDE OR MARGINAL MARGINS HAVE BETTER LOCAL RECURRENCE AND SURVIVAL OUTCOMES THAN INTRALESIONAL RESECTIONS OF PRIMARY BONE TUMOURS OF THE SPINE - THE RESULTS OF A MULTICENTRE STUDY C G Fisher; D Saravanja; P W Clarkson; H Zhang; M Boyd; R Fox; J Hurlbert; R Rampersaud; S Lewis; M FS Dvorak |
| 35 | #39331 FUNCTIONAL RESULTS OF WRIST ARTHRODESIS AFTER RESECTION OF GIANT CELL TUMOUR OF THE DISTAL RADIUS ARE EQUIVALENT WITH VASCULARISED OR NON-VASCULARISED TISSUE TRANSFER P W Clarkson; K L Sandford; A E Phillips; A M Griffi n; P C Ferguson; J S Wunder; B A Masri; T Goetz |
| 35 | #39335 A COMPARISON OF SHORT-TERM OUTCOMES IN PATIENTS TREATED FOR EPIMETAPHYSEAL BENIGN-AGGRESSIVE BONE LESIONS USING POLYMETHYLMETHACRALATE (PMMA) OR BONE GRAFT WITH/ WITHOUT PMMA A D. Uglialoro; H Goodman; K S. Beebe; F R. Patterson; J Benevenia |
| 36 | #39341 CUTANEOUS RADIATION-ASSOCIATED ANGIOSARCOMA OF THE BREAST: POOR PROGNOSIS IN A RARE BUT INCREASINGLY MORE COMMON CONSEQUENCE OF RADIATION THERAPY ADMINISTERED FOR PRIMARY BREAST CANCER TREATMENT E A Morgan; C M Mery; D E Kozono; J E Butrynski; E H Baldini; S George; A F Nascimento; C P Raut |
| 36 | #39342 LOCAL RECURRENCE FROM SOFT TISSUE SARCOMA: IS THERE A WAY OUT R E Turcotte; A Sarantis; A Adoubali; M H Isler; D Roberge |
| 36 | #39344 CURETTAGE AND CRYOSURGICAL TREATMENT OF CARTILAGINOUS BONE TUMORS OF UNCERTAIN MALIGNANT POTENTIAL R S Avedian; R Chiu; D McCall; D Mohler |
| 37 | #39345 MINIMALLY INVASIVE SURGICAL TREATMENT USING NEWLY DEVISED MULTI-HOLED SCREWS AND BONE CEMENT FOR FEMORAL NECK LESION IN PATIENTS WITH MULTIPLE METASTASES H Kang; J Kim; Y Roh; I Han; H Kim |
| 37 | #39347 ADVANTAGE OF COMPUTED TOMOGRAPHY FOR MONITORING PULMONARY METASTASES AFTER SURGERY FOR SOFT TISSUE SARCOMA H Cho; I Han; H Kim |
| 37 | #39358 UNDIFFERENTIATED PLEOMORPHIC SARCOMAS OF THE PERITONEAL CAVITY AND RETROPERITONEUM: A REPORT ON SURVIVAL OUTCOMES George W Dittrick, Alfredo A Santillan, Vernon K Sondak, David Cheong, G Douglas Letson, Marilyn Bui, Scott Antonia, Jonathan S Zager, Ricardo J Gonzalez |
| 38 | #39372 SUPERFICIAL SOFT TISSUE SARCOMAS: FAVORABLE OUTCOME INDEPENDENT OF OTHER PRIMARY TUMOR FEATURES R Burke; J M. Kane III |
| 38 | #39395 FUNCTIONAL OUTCOME AND SEXUAL DYSFUNCTION FOLLOWING RESECTION OF THE PELVIS AND SACRUM S Marong; A Cizik; J Weisstein; T Scharschmidt; E U Conrad |
| 38 | #39401 COMPLICATIONS AND IMPLANT SURVIVAL FOLLOWING ENDOPROSTHETIC RECONSTRUCTION: 243 CASES TREATED AT A SINGLE INSTITUTION A Shehadeh; J B. Noveau; R M. Henshaw |
| 39 | #39406 RADIOGRAPHIC RESPONSE OF UNICAMERAL BONE CYSTS TREATED WITH DEMINERALIZED BONE MATRIX A Shehadeh; J B. Noveau; R M. Henshaw |
| 39 | #39432 MULTIVARIATE PREDICTORS OF OUTCOME IN A SINGLE INSTITUTION 10 YEAR SERIES OF 115 PATIENTS WITH LEIOMYOSARCOMA J A Abraham; E H Baldini; M J Weaver; D J Zurakowski; J E Ready |
| 39 | #39437 COMPUTER AIDED NAVIGATION CAN BE USED FOR PELVIS BONE SARCOMA RESECTION J A Abraham; J E Ready |
| 40 | #39441 USE OF A CUSTOM PROSTHESIS WITH A MODULAR REVISION FEMORAL STEM IN TYPE- 2 INTERNAL HEMIPELVECTOMIES FOR THE RESECTION OF PELVIC SARCOMAS. O Binitie; E Henderson; R Gonzalez; G Douglas Letson; D Cheong |
| 40 | #39451 SURGICAL TECHNIQUES , GUIDELINES AND FUNCTIONAL RESULTS OF ENDOPROSTHETIC REPLACEMENT OF THE SCAPULA: IS SCAPULAR ENDOPROSTHETIC REPLACEMENT SUPERIOR TO HUMERAL SUSPENSION ? M Miles Malawer; J Wittig; J Bickels; T Pritch; T Ben-Tov1 |
| 40 | #39464 DISTAL FEMORAL RECONSTRUCTION FOR THE TREATMENT OF MALIGNANT BONE TUMORS G Marulanda; B Palumbo; E Hhnderson; D Cheong; D Letson |
| 41 | #39465 QUADRICEPS SPARING LATERAL APPROACH FOR DISTAL FEMORAL RECONSTRUCTION G Marulanda; E Henderson; D Cheong; D Letson |
| 4:30 - 5:30 p.m. | Molecular Pathology Moderator: Paolo dei Tos |
| 41 | #39253 ANGIOSARCOMAS HAVE UNIQUE RNA EXPRESSION PROFILES BASED ON SITE AND ETIOLOGY, WITH POSSIBLE IMPLICATIONS FOR THERAPY C R. Antonescu; A Yoshida; T Guo; N Cheng; L Zhang; N P. Agaram; L Qin; M F. Brennan; S Singer; R G. Maki |
| 41 | #39238 A GENE-EXPRESSION SIGNATURE RELATED TO TUMOR GENOME COMPLEXITY IS A PREDICTOR OF METASTASIS OUTCOME IN NONTRANSLOCATION RELATED SARCOMAS F Chibon; P Lagarde; S Salas; G Perot; V Brouste; B Bui; J Coindre; A Aurias |
| 42 | #39286 EVALUATION OF THE CLASSIFICATION PLEOMORPHIC LIPOSARCOMA. AN IMMUNOHISTOCHEMICAL AND MOLECULAR BIOLOGICAL ANALYSIS. R S.A. de Vreeze; F van Coevorden; I H.G. Tielen; H J. Ruijter; P M. Nederlof; R L. Haas; D de Jong |
| 42 | #39434 EARLY HISTOLOGICAL CHANGES IN GASTROINTESTINAL STROMAL TUMORS EXPOSED TO SHORT-TERM, PREOPERATIVE IMATINIB THERAPY W Wang; B P Rubin; H Choi; K K Hunt; R E Pollock; R S Benjamin; D Yang; D G Reynoso; J C Trent; A J F Lazar |
| Friday, November 6, 2009 |
|
| 8:00 - 9:00 a.m. |
Surgical Oncology Moderator: Frits van Coevorden |
| 45 | #39339 SUBTYPE SPECIFIC POST-OPERATIVE NOMOGRAM FOR PATIENTS AFFECTED BY PRIMARY RETROPERITONEAL SOFT TISSUE SARCOMA. A Gronchi; I Arduino; R Miceli; M Berselli; L Mariani; E Biganzoli; M Fiore; P Collini; F Grosso; P Giovanni Casali |
| 45 | #39364 IN-VIVO IMAGING OF SARCOMA IN MICE: TOWARDS REAL-TIME, INTRAOPERATIVE TUMOR BED ASSESSMENT B E. Brigman; J M. Ferrer; J K. Mito; C Lee; W C Eward; R D. Dodd; Y Kim; L F Marshall; A Dash; J Quinn; L Dodd; D Dankort; W David Lee; M McMahon; L Griffi th; M G Bawendi; D G. Kirsch |
| 45 | #39305 FRONTLINE AGGRESSIVE SURGICAL APPROACH TO PRIMARY RETROPERITONEAL SOFT TISSUE SARCOMA: A MORBIDITY / MORTALITY ANALYSIS FROM A MULTI-INSTITUTIONAL RETROSPECTIVE REVIEW. M Fiore; S Bonvalot; R Miceli; S Causeret; L Mariani; H Bouzaiene; C Colombo; C Le Péchoux; A Gronchi |
| 46 | #39308 PRIMARY EXTREMITY SOFT TISSUE SARCOMA: A MORE LIBERAL MULTIMODALITY APPROACH MAY HAVE IMPROVED SURVIVAL OVER TIME. M Berselli; M Fiore; F Grosso; L Mariani; R Bertulli; P Collini; L Lozza; S Stacchiotti; E Pennacchioli; P Giovanni Casali; A Gronchi |
| 46 | #39231 ANGIOSARCOMA: CLINICAL AND MOLECULAR INSIGHTS G Lahat1; L xiao1; K Smith1; T Phung2; C Zou1; R Pollock1; R Benjamin1; k hunt1; D Lev1 9:00 - 10:15 a.m. Surgical/Orthopaedic Oncology Pompeii Ballroom Moderator: Francis Hornicek |
| 46 | #39359 MYXOFIBROSARCOMA: A RETROSPECTIVE ANALYSIS OF 158 PATIENTS R Sanfi lippo; F Grosso; E Pennacchioli; M Barisella; M Fiore; C Morosi; P Collini; P Giovanni Casali; A Gronchi |
| 46 | #39336 EFFECTS OF NEOADJUVANT CHEMOTHERAPY ON IMAGE-DIRECTED PLANNING OF SURGICAL RESECTION FOR DISTAL FEMUR OSTEOSARCOMA K B Jones; B Lam; A Griffi n; M Biddulph; K Saidi; Y Gortzak; M Al-Yamani; S Hopyan; B Deheshi; P C Ferguson; L White; J S Wunder |
| 47 | #39292 RISK BASED FOLLOW-UP REGIMEN FOR PATIENTS WITH HIGH GRADE OSTEOSARCOMA # A Abudu |
| 47 | #39351 CHONDROSARCOMA OF THE CHEST WALL: PRIMARY DIAGNOSTICS IS DECISIVE FOR OUTCOME H Bauer; B Widhe |
| 47 | #39471 DEVELOPMENT OF COMPUTER ASSISTED SURGERY FOR ORTHOPAEDIC ONCOLOGY APPLICATIONS: PRELIMINARY REPORT OF THE FIRST AMERICAN CASE SERIES D Cheong; D Nuggent; E Henderson; G Marulanda; D Letson |
| 48 | #39255 CHONDROSARCOMA OF BONE: SURVIVAL ANALYSIS AND PROGNOSTIC FACTORS IN A SERIES OF 155 PATIENTS TREATED AT A SINGLE INSTITUTION P Tunn; D Andreou; S Fehlberg; M Werner; P Reichardt |
| 10:45 - 11:45 a.m. |
Herman Suit Lecture Support provided by the Spitz Family Fund Speaker: Matt van de Rijn |
| 11:45 a.m. - 1:00 p.m. | New Targets Moderator: Lee Helman |
| 48 | #39246 TARGETING ALK RECEPTOR TYROSINE KINASE (RTK) IN INFLAMMATORY MYOFIBROBLASTIC TUMOR (IMT) J E Butrynski; D R D'Adamo; A Wolanski; L Ahn; L Chiambalero; K Stolgitis; P A Janne; E L Kwak; J W Clark; K Wilner; J Christensen; G D Demetri; R G Maki; S I Geoffrey |
| 48 | #39313 PRELIMINARY RESULTS FROM A PHASE 2 STUDY OF ARQ 197 IN PATIENTS WITH MICROPHTHALMIA TRANSCRIPTION FACTOR FAMILY (MIT) ASSOCIATED TUMORS A J. Wagner; G D. Demetri; E Choy; A S. Pappo; S DuBois; J Geller; L Rosen; N Senzer; K Albritton; F Chai; D Ferrari; J M. Goldberg |
| 49 | #39254 DEVELOPMENT OF HLA-A2 AND HLA-A24-RESTRICTED PEPTIDE VACCINES FROM A NOVEL OSTEOSARCOMA ANTIGEN, PAPILLOMAVIRUS BINDING FACTOR S Kawaguchi; T Tsukahara; T Wada; S Nagoya; M Kaya; T Torigoe; N Sato; T Ishii; S Tatezaki; T Yamashita |
| 49 | #39251 HISTOLOGIC EFFECTS OF DENOSUMAB ON GIANT CELL TUMOR (GCT) OF THE BONE M Roudier; I Jacobs; R Soriano; A Jacob; S D Nelson; W C Dougall; S Jun |
| 49 | #39225 HIGH-THROUGHPUT MUTATION PROFILING OF OSTEOSARCOMA PRIMARY TUMORS AND CELL LINES IDENTIFIES NEW MUTATIONS IN PREVIOUSLY UNASSOCIATED ONCOGENES AND TUMOR SUPRESSOR GENES E Choy; L MacConail; L Garraway; D Harmon; F Hornicek; Z Duan |
| 50 | #39252 PEDF: PRECLINICAL EVALUATION OF EFFICACY AGAINST OSTEOSARCOMA C R. Dass; T Akiyama; P Choong |
| 50 | #39263 A NOVEL TARGET FOR TREATMENT OF CHORDOMA: STAT3 C Yang; J Schwab; A Schoenfeld; F Hornicek; K Wood; P Nielsen; E Choy; H Mankin; Z Duan Mass. General Hospital, Boston, MA, United States |
| 2:00 - 3:00 p.m. | Adolescent and Young Adult Sarcomas (AYA) Moderator: Piero Picci |
| 50 | #39452 THE EUROPEAN AND AMERICAN OSTEOSARCOMA STUDY GROUP PROTOCOL, EURAMOS-1: SUCCESSFUL TRANSATLANTIC COOPERATION IN OSTEOSARCOMA D Carrle; S Bielack; M Sydes; T Butterfass-Bahloul; G Calaminus; G Jovic; N Marina; A Oellers; M Perisoglou; S Smeland; J Whelan; M Bernstein |
| 51 | #39279 A RANDOMIZED TRIAL OF NEOADJUVANT CHEMOTHERAPY WITH METHOTREXATE (MTX), CISPLATIN (CDP) AND DOXORUBICIN (ADM), WITH OR WITHOUT IFOSFAMIDE (IFO) FOR NON-METASTATIC OSTEOSARCOMA OF THE EXTREMITY: ANALYSIS OF HISTOLOGIC RESPONSE AND TOXICITY. S Ferrari; G Cefalo; A Tamburini; A Comandone; A Brach del Prever; P Casali; M Alberghini; E Palmerini; A Longhi; M Mercuri; R Capanna; S Mapelli; P Picci; G Bacci |
| 51 | #39314 EWS:ERG PREDICT RESPONSE AND PTEN LOSS PREDICTS RESISTANCE TO SELECTIVE IGF1R INHIBITION IN EWING'S SARCOMA W D. Tap; J Dering; C Ginther; D Wai; S Plaisier; S Dry; N Bernthal; K Clarke; C Tung; A J. Desai; S Bajaj; H Wu; T Graeber; F Calzone; T Triche; D J. Slamon; F C. Eilber |
| 52 | #39407 SYSTEMIC THERAPY IN SOLITARY FIBROUS TUMOUR A Constantinidou; R L Jones; M Scurr; O Al-Muderis; I Judson |
| 3:00 - 4:15 p.m. | Pediatric Oncology, Biology, New Targets Moderator: Stephen Lessnick |
| 52 | #39275 METFORMIN INHIBITS THE METASTATIC PHENOTYPE OF OSTEOSARCOMA CELLS:MECHANISMS AND TRANSLATIONAL STUDIES M Ahluwalia; S Hong; J Briggs; L Ren; C Khanna |
| 52 | #39461 SHEDDING NEW LIGHT ON THE ROLE OF AKT IN THE METASTATIC BIOLOGY OF OSTEOSARCOMA S Hong; L Ren; C Khanna |
| 53 | #39198 THERAPEUTIC TARGETING OF EWS-FLI1: SMALL MOLECULE PROTEINPROTEIN INTERACTION INHIBITORS PREVENT XENOGRAFT GROWTH J Toretsky; H Verda Erkizan; Y Kong; M Merchant; J Barber-Rotenberg; M Brown; A Uren |
| 53 | #39261 IDENTIFICATIN OF DUAL-SPECIFICITY TYROSINE-(Y)- PHOSPHORYLATION REGULATED KINASE 1B (DYRK1B) AS A POTENTIAL THERAPEUTIC TARGET IN OSTEOSARCOMA Z Duan; C Yang; D Ji; E Weinstein; E Choy; H Mankin; F J Hornicek |
| 53 | #39369 LOSS OF FUNCTION SCREEN IN RHABDOMYOSARCOMA DEMONSTRATES CRKL IS REQUIRED FOR RMS GROWTH. C L Yeung; V N Ngo; X Wan; S Kim; P Grohar; C Khanna; L M Staudt; L J Helman |
| 54 | #39438 FLOW CYTOMETRIC DETECTION OF CD99-POSITIVE / CD45-NEGATIVE CELLS IN THE BONE MARROW OF PATIENTS WITH EWING SARCOMA S G DuBois; L Epling; K K. Matthay; R Goldsby; C Braunreiter; E Sinclair; S L. Lessnick |
| 4:45 - 5:00 p.m. | Poster Discussion 2—Biology Moderator: Dave Viskochil |
| 54 | #38456 ANTITUMORIGENIC EFFECT OF BRAIN PROLINE RICH POLYPEPTIDE-1 IN HUMAN CHONDROSARCOMA K A Galoian; S P Scully; A A Galoyan |
| 54 | #38669 WHO WATCHES THE WATCHMEN: NOVEL IMAGE GUIDED VISUALIZATION OF EXPERIMENTAL CELLULAR-BASED IMMUNOTHERAPY AGAINST SOFT TISSUE SARCOMA (STS) S Eric Finkelstein; D I. Gabrilovich; I M. Ahmed; J Ahmed; C Berman; M M. Bui; A Chau; D Cheong; E Eikman; R J. Gonzalez; R V. Heysek; D A. Johnson; V K. Sondak; R R. Szekely; J S. Zager; G Douglas Letson; S J. Antonia |
| 55 | #39208 DUAL-ENERGY CT FOR THERAPY MONITORING OF PATIENTS WITH ADVANCED GIST UNDER TARGETED THERAPY: INITIAL RESULTS M Schlemmer; N Schramm; K Nikolaou; C Becker; M Reiser; F Berger |
| 55 | #39217 PHASE I/II AND PHASE II STUDIES OF TARGETED GENE DELIVERY IN VIVO: REXIN-G FOR CHEMOTHERAPY RESISTANT SARCOMA AND OSTEOSARCOMA S P Chawla; V S Chua; L Fernandez; D Quon; A Saralou; W C Blackwelder; F L Hall; E M Gordon |
| 55 | #39218 DAXX MRNA CONTENT PREDICTS CASP8 TRANSCRIPTION IN PRIMARY SARCOMAS D E Joyner; S H Trang; T A Damron; A J Aboulafi a; R A Ward; K B Jones; R Randall |
| 56 | #39226 PHASE I/II STUDY OF TH-302 COMBINED WITH DOXORUBICIN IN SOFT TISSUE SARCOMA (STS): PRELIMINARY RESULTS K N Ganjoo; L D Cranmer; S Kroll; V K Langmuir; S P Chawla |
| 56 | #39228 TRAIL AND DOXORUBICIN SYNERGISTICALLY DECREASE STS GROWTH AND METASTASIS IN VIVO: A STRATEGY TARGETING BOTH TUMOR AND MICROENVIROMENT D Katz; S Wang; W Ren; J D Hazle; R E Pollock; D Lev |
| 56 | #39233 INCREASED VEGF-C EXPRESSION IS INSUFFICIENT TO INDUCE LYMPHATIC METASTASIS IN HUMAN SOFT TISSUE SARCOMAS G Lahat; A Lazar; W Wang; Q Zhu; K Hunt; R Pollock; D Lev |
| 57 | #39235 A PHASE II RANDOMIZED CONTROLLED TRIAL OF PALIFOSFAMIDE PLUS DOXORUBICIN VS. DOXORUBICIN IN PATIENTS WITH SOFT TISSUE SARCOMA S Chawla; M Mita; C Verschraegen; C Ryan; A Santoro; J Stevens; J Lewis; R Maki; P Investigators |
| 57 | #39267 HISTONE DEACETYLASE INHIBITO (HDACI) PCI-24781 SYNERGIZE CHEMOTHERAPEUTIC DRUGS INDUCED APOPTOSIS IN MULTIDRUG RESISTANT SARCOMA CELLS C Yang; E Choy; F Hornicek; K Wood; J Schwab; X Liu; H Mankin; z Duan |
| 57 | #39270 DYNAMIC MODULARITY OF PATHWAYS IN OSTEOSARCOMA METASTASIS A Goudarzi; J Wunder; N Gokgoz; T Yan; I Andrulis |
| 58 | #39309 OSTEOCHONDROMA AND PERIPHERAL CHONDROSARCOMA: REDEFINITION OF EXT GENES ROLE E Pedrini; M Zuntini; A Parra; M Alberghini; F Sgariglia; L Sangiorgi |
| 58 | #39310 TRABECTEDIN PHASE II CLINICAL TRIALS: POOLED ANALYSIS OF SAFETY A Cioffi ; A LeCesne; J Blay; S Delaloge; A Yovine; R Maki; A Nieto; J Jiao; G Demetri |
| 58 | #39312 EMMPRIN EXPRESSION IS ASSOCIATED WITH METASTATIC PHENOTYPE IN OSTEOSARCOMA I Han; M Lee; J Kim; H Kim |
| 58 | #39323 PHASE II STUDY OF INTRAVENOUS REOLYSIN (WILD TYPE REOVIRUS) IN PATIENTS WITH BONE AND SOFT TISSUE SARCOMA METASTATIC TO LUNG M Mita; K Sankhala; J Sarantopoulos; A Mita; A Carmona; S Goel; R Chugh; K Mettinger; M Coffey; S Okuno |
| 59 | #39338 EMERGENT PROPERTIES OF EWS/FLI REGULATION VIA GGAA MICROSATELLITES IN EWINGS SARCOMA K Gangwal; S L. Lessnick |
| 59 | #39346 RESPONSE EVALUATION CRITERIA IN SOLID TUMORS (RECIST) IN SOFT TISSUE SARCOMA OF EXTREMITY Y Morimoto; Y Yoneda; A Yoshida; S Itani; T Kunisada; T Ozaki |
| 59 | #39352 ROLE OF POLYCOMB GROUP GENE PHC3 IN OSTEOSARCOMA TUMORIGENESIS S Iwata; H Takenobu; A Nakagawara; T Kamijo |
| 60 | #39354 IDENTIFICATION OF DIFFERENTIALLY EXPRESSED MICRORNAS IN LIPOSARCOMA SUBTYPES C Gits; M den Bakker; K Verhoef; M Jonkers; T Boersma; J Verweij; S Sleijfer; E Wiemer |
| 60 | #39356 HISTONE DEACETYLASE INHIBITOR COMBINED WITH DNA DEMETHYLATION DRUG SUPPRESSED THE GROWTH OF SYNOVIAL SARCOMA CELLS A Yoshida; C Sato; Y Morimoto; S Itani; T Sasaki; T Kunisada; T Ozaki |
| 60 | #39373 TROMBOEMBOLIC EVENTS IN GIST PATIENTS RECEIVING SUNITINIB P Coco; E Fumagalli; C Piovesan; R Bertulli; C Morosi; P Giovanni Casali |
| 61 | #39377 SAFETY OF SUNITINIB TREATMENT INITIATION 24 HOURS FOLLOWING A FINAL DOSE OF IMATINIB IN PATIENTS WITH ADVANCED GIST E Fumagalli; P Coco; A Bello; C Blanckmeister; P G. Casali |
| 61 | #39388 TRIGGERING OF CD99 INDUCES APOPTOSIS OF EWING?S SARCOMA CELLS THROUGH RE-ACTIVATION OF P53 FUNCTIONS K Scotlandi; C Guerzoni; M Manara; P Picci |
| 61 | #39393 IDENTIFICATION AND CHARACTERIZATION OF COPY NUMBER VARIATIONS IN OSTEOSARCOMA N Gokgoz; J S Wunder; I L Andrulis |
| 61 | #39400 CUTANEOUS AND SUBCUTANEOUS EWING SARCOMAS: GOOD PROGNOSIS IN A RETROSPECTIVE SERIES OF 17 PATIENTS A Marrari; P Dileo; C Piovesan; E Puma; R Bertulli; A Gronchi; M Fiore; P Olmi; L Lozza; P Giovanni Casali |
| 62 | #39404 RECHALLENGE WITH IMATINIB IN GIST PATIENTS RESISTANT TO SECOND OR THIRD LINE THERAPY E Fumagalli; P Coco; C Morosi; P Dileo; R Bertulli; A Gronchi; P Giovanni Casali |
| 62 | #39410 BONE METASTASES IN GASTROINTESTINAL STROMAL TUMOUR (GIST): AN UNDERESTIMATED OCCURRENCE E Fumagalli; P Coco; A Messina; R Bertulli; L Lozza; P Olmi; P Giovanni Casali |
| 62 | #39417 DISCREPANCIES IN CURRENT ADJUVANT THERAPY OF GASTROINTESTINAL STROMAL TUMORS (GIST) ACROSS REFERENCE CENTERS IN THE WORLD P Casali |
| 62 | #39418 CHEMOTHERAPY IN CLEAR CELL SARCOMA R L Jones; A Constantinidou; M Scurr; O Al-Muderis; I Judson |
| 63 | #39419 PET IMAGING FOR SARCOMA DRUG RESISTANCE ACTIVITY J Eary; J Link; E U Conrad, III |
| 63 | #39421 IMPLEMENTATION OF A NURSE MEDIATED BLOG FOR SARCOMA PATIENTS FROM ONE ACADEMIC CANCER CENTER A S Potter; T Colon; K Polson; C Raut; M Lapidus; S George |
| 63 | #39443 CHARACTERIZATION OF GIANT CELL TUMOR IN VITRO Y Gortzak; J Wunder; P Ferguson; B Deheshi; R Turcotte; J Werier; R Kandel 63 #39448 OSTEOSARCOMA DEVELOPMENT AND METASTASIS GENE DISCOVERY B Scott Moriarity; D A Largaespada |
| 64 | #39453 COMPASSIONATE USE ADMINISTRATION OF TRABECTEDIN IN A 24- HOUR INFUSION EVERY 3 WEEKS (Q3W) IN PRETREATED ADVANCED SARCOMA PATIENTS A Yovine; I Robert Judson; J Blay; P Giovanni Casali; J Misset; B Louis Samuels; C Lebedinsky; J Fernando Perez; P Zintl; P Schoffski |
| 64 | #39454 EFFICACY OF CONVENTIONAL CHEMOTHERAPEUTICS IN ERADICATING SARCOMA TUMOR INITIATING (CANCER STEM) CELLS Q Wei; Y Wang; J Hu; F Zheng; R Poon; B Alman; J Wunder |
| 64 | #39462 A RANDOMIZED, PHASE II STUDY OF PERIFOSINE (P) PLUS IMATINIB (IM) FOR PATIENTS WITH IMATINIB-RESISTANT GASTROINTESTINAL STROMAL TUMOR (GIST) A P. Conley; M S. Park; D M. Araujo; J A. Ludwig; V Ravi; B L. Samuels; H Choi; S Patel; R S. Benjamin; J C. Trent |
| 65 | #39473 DIFFERENTIAL EXPRESSION OF MICRORNA AFTER IMATINIB IN GIST A P. Conley; D Reynoso; D Cogdell; L Hu; L Nolden; W Zhang; R Benjamin; J C. Trent |
| 65 | #39475 LOW DOSES AND 24-HOUR PERFUSION WITH TRABECTEDIN IN HEAVILY PRETREATED SOFT TISSUE SARCOMA (STS) PATIENTS: A PARTICULAR TOXICITY PROFILE. J Martin-Broto; A Gutierrez; M Ramirez; C Martorell; P Luna; M Navarro; R Alemany; J Martinez Serra |
| 65 | #39509 PAR1 IS UPREGULATED AND PROMOTES INVASION IN A MURINE MODEL OF METASTATIC OSTEOSARCOMA J P Sand, K A Janeway, J Perry, S H Orkin |
| 5:00 - 5:30 p.m. |
Young Investigator Award Winners Moderators: Shreyas Patel and Bob Maki |
| 66 | #39416 INTEGRATIVE AND FUNCTIONAL CHARACTERIZATION OF THE SOFT TISSUE SARCOMA GENOME J Barretina; B S Taylor; A H Ramos; M Lagos-Quintana; S Banerji; P L DeCarolis; B A Weir; A Ho; D Y Chiang; B Reva; C Hatton; J E Major; K Cibulskis; R G Maki; G K Schwartz; C R Antonescu; M Ladanyi; C Sander; M Meyerson; S Singer |
| 66 | #39276 SYNTHETIC LETHALITY SIRNA SCREENING TO IDENTIFY NOVEL THERAPEUTIC TARGETS IN EWING SARCOMA J Potratz; M Pollak; H Jürgens; P Sorensen |
| Saturday, November 7, 2009 |
|
| 8:00 - 9:00 a.m. | Medical Oncology Moderator: Mikael Eriksson |
| 69 | #39239 FINAL ANALYSIS OF A NON-COMPARATIVE PHASE II STUDY OF MULTI TARGET ENZYME INHIBITOR PEMETREXED IN PATIENTS (PTS) WITH REFRACTORY SOFT TISSUE SARCOMA (STS) ? GERMAN SARCOMA GROUP / AIO 005 J Thomas Hartmann; S Bauer; S Schädel; I Meisinger; B Kasper; H Kopp; F Mayer; V Grünwald |
| 69 | #39240 RISK OF RADIATION-INDUCED SARCOMA (RIS): DATA OF A POPULATIONBASED REGISTRY OF 29 931 IRRADIATED PATIENTS (PTS) IN SOUTH WEST GERMANY J Thomas Hartmann; H Hecker; H Kopp; F Mayer; J Classen; A Koenigsrainer; D Wallwiener; M Bamberg |
| 69 | #39250 BEVACIZUMAB FOR THE TREATMENT OF ANGIOSARCOMA: AN OPEN LABEL MULTICENTER PHASE II STUDY M Agulnik; S H Okuno; M von Mehren; B Jovanovic; B Brockstein; R Benjamin; A Evens |
| 70 | #39455 RELATIVE RISKS FOR CANCERS IN THE NEUROFIBROMATOSIS POPULATION IN UTAH D Viskochil, L Cannon-Albright, D Stevenson |
| 9:00 - 10:15 a.m. | GIST Moderator: Jonathan Trent |
| 70 | #39394 IMATINIB MESYLATE MODULATES REGULATORS OF TUMOR CELL QUIESCENCE IN GASTROINTESTINAL STROMAL TUMOR CELLS J A Parry; M F Brown; D Seneviratne; S Duensing; A Duensing |
| 70 | #39457 PRO-APOPTOTIC ACTIVITY OF BORTEZOMIB IN GASTROINTESTINAL STROMAL TUMOR (GIST) CELLS S Bauer; J A Parry; T Muehlenberg; P Chatterjee; S Kuan; J A Fletcher; S Duensing; A Duensing |
| 71 | #39288 STEADY-STATE PLASMA IMATINIB LEVELS IN 124 GIST PATIENTS: DISTRIBUTION, DOSE, DOSE ESCALATION, AND RESPONSE L K Nolden; L Shum; A Dumont; S Patel; D M Araujo; J A Ludwig; V Ravi; S George; S Vadhan- Raj; R S Benjamin; J C Trent |
| 71 | #39334 HIGH DENSITY DNA ARRAY ANALYSIS REVEALS DISTINCT GENOMIC PROFILES IN A SUBSET OF GASTROINTESTINAL STROMAL TUMORS M G. Belinsky; Y V. Skorobogatko; L Rink; J Pei; K Q. Cai; L A. Vanderveer; D Riddell; E Merkel; C Tarn; B L. Eisenberg; M von Mehren; J R. Testa; A K. Godwin |
| 71 | #39300 MICROSCOPIC GASTROINTESTINAL STROMAL TUMORS (MICGIST): CLINICOPATHOLOGICAL AND MOLECULAR ANALYSIS OF 85 CASES. S Rossi; D Gasparotto; L Toffolatti; C Sartor; G Gallina; A Marzotto; R Talamini; G Mazzoleni; I Bearzi; L Messerini; C Cantaloni; M Barbareschi; R Maestro; A P Dei Tos |
| 72 | #39408 COMPLETE LOSS OF SUCCINATE DEHYDROGENASE B (SDHB) PROTEIN IN PEDIATRIC GASTROINTESTINAL STROMAL TUMORS (GIST) K Anne Janeway; B Liegl; V Nose; J L Hornick; J Barretina; P L Dahia; J A Fletcher |
| 11:00 a.m. - 12:00 p.m. | Nina Axelrad Lecture Moderator: Laurence Baker |
| 12:00 - 12:45 p.m. | Rare Sarcomas - DFSP Moderator: Ian Judson |
| 72 | #39321 DERMATOFIBROSARCOMA PROTUBERANS (DFSP) AND FIBROSARCOMATOUS (HIGH-GRADE) DFSP: A MONO-INSTITUTIONAL RETROSPECTIVE ANALYSIS E Palmerini; M Gambarotti; E L. Staals; A Longhi; G Sieberova; M Cesari; M E. Abate; P Picci; M Mercuri; M Alberghini; S Ferrari |
| 72 | #39271 METICULOUS PATHOLOGIC EVALUATION TO ENSURE NEGATIVE MARGINS FACILITATES A LOW RISK OF LOCAL RECURRENCE OF DERMATOFIBROSARCOMA PROTUBERANS (DFSP) M M. Bui; J L. Messina; J M. Farma; S S. Marzban; V K. Sondak; D Letson; J S. Zager |
| 73 | #39353 IMATINIB ACTIVITY IN DERMATOFIBROSARCOMA PROTUBERANS (DFSP)-DERIVED FIBROSARCOMA (FS) S Stacchiotti; A Marrari; F Pedeutour; P Collini; T Negri; E Palassini; C Morosi; U Pastorino; A Gronchi; S Pilotti; P Giovanni Casali |
| 1:45 - 2:30 p.m. | Rare Sarcomas Moderator: Dennis Priebat |
| 73 | #39396 PROXIMAL-TYPE EPITHELIOID SARCOMAS: A RETROSPECTIVE ANALYSES OF 31 PATIENTS C Piovesan; P Dileo; E Puma; A Marrari; R Bertulli; M Fiore; P Olmi; A Gronchi; P Giovanni Casali |
| 73 | #39268 CLINICAL AND MOLECULAR INSIGHTS INTO EPITHELIOID SARCOMA A Kishor Sakharpe; G Lahat; P Rao; V Ravi; J Hornick; A J Lazar; D Lev |
| 74 | #39415 CHEMOTHERAPY IN EPITHELIOID SARCOMA R L Jones; A Constantinidou; M Scurr; O Al-Muderis; I Judson |
| 74 | #39402 HISTIOCYTIC AND DENDRITIC CELL NEOPLASMS (HDCN): CLINICAL BEHAVIOUR AND RESPONSE TO CHEMOTHERAPY S Stacchiotti; A Gentile; F Grosso; E Palassini; P Collini; R Bertulli; P Di Leo; A Messina; C Morosi; A Gronchi; P Giovanni Casali |
| 2:30 - 3:45 p.m. | Radiation Oncology Moderator: Anders Krarup-Hansen |
| 74 | #39282 PRE-OPERATIVE RADIOTHERAPY IMPROVES OVERALL SURVIVAL IN GENERAL SOFT-TISSUE SARCOMA: MULTI-INSTITUTIONAL ANALYSIS OF 3,110 PATIENTS S Sampath; T E. Schultheiss; Y J. Hitchcock; R Lor Randall; D C. Shrieve; J Y.C. Wong |
| 75 | #39205 A SYSTEMATIC REVIEW AND META-ANALYSIS OF ONCOLOGIC OUTCOMES IN PRE- VS POST-OPERATIVE RADIATION IN LOCALIZED RESECTABLE SOFT-TISSUE SARCOMA E Al-Absi; F Farokkhyar; M Patel; T Corbett; R Sharma; M Ghert |
| 75 | #39290 THE INFLUENCE OF AGE ON MORBIDITY IN PRIMARY HIGH GRADE SARCOMA OF THE EXTREMITY K M. Alektiar; M F. Brennan; S Singer |
| 76 | #39392 EXAMINING THE RELATIONSHIP BETWEEN THE LOCATION OF LOCAL TUMOUR RECURRENCE AND THE RADIOTHERAPY TREATMENT VOLUME FOR EXTREMITY SOFT TISSUE SARCOMA PATIENTS TREATED WITH EXTERNAL BEAM RADIOTHERAPY COMBINED WITH LIMB-SALVAGE SURGERY C I Dickie; A Parent; A Griffi n; M Sharpe; P Chung; C Catton; P Ferguson; J Wunder; B O'Sullivan |
| 76 | #39242 15 YEARS EXPERIENCE OF MANAGEMENT OF MALIGNANT PHYLLODES TUMOR AND BREAST SARCOMA AT PRINCESS MARGARET HOSPITAL N G Patil; C N Catton; B O'Sullivan; R Dinniwell; A Griffi n; P C Ferguson; R Gladdy; D McCready; M Blackstein; A Gupta; L W Le; P W Chung |
| 4:15 - 4:30 p.m. |
Poster Discussion 3 – Medical-Pediatric Oncology Moderator: Scott Schuetze |
| 76 | #38668 PROSPECTIVE PHASE I/II TRIAL OF INTRATUMORAL DENDRITIC CELL VACCINE IMMUNOTHERAPY (DC) COMBINED WITH EXTERNAL BEAM RADIATION (EBRT) FOR NEO-ADJUVANT TREATMENT OF SOFT TISSUE SARCOMA S Eric Finkelstein; D I. Gabrilovich; J Ahmed; M M. Bui; M J. Cotter; D Cheong; R J. Gonzalez; R V. Heysek; B C. Lenox; V K. Sondak; R R. Szekely; J S. Zager; G Douglas Letson; S J. Antonia |
| 77 | #39179 INTERIM ANALYSIS OF A PHASE II STUDY OF NEOADJUVANT BEVACIZUMAB AND RADIATION THERAPY FOR RESECTABLE SOFT TISSUE SARCOMAS S S. Yoon; D Karl; C Rothrock; E Choy; D C. Harmon; F J. Hornicek; D S. Springfi eld; K A. Raskin; A E. Rosenberg; G Petur Nielsen; A Kambadakone; D Sahani; J Dreyfuss; P J. Park; D P. Kirsch; Y Chen; T F. DeLaney |
| 77 | #39199 ONCOGENESIS AND CLINICAL ASPECTS OF MIXED-TYPE LIPOSARCOMA: A RADIOLOGICAL, HISTOPATHOLOGICAL AND MOLECULAR BIOLOGICAL ANALYSIS R S.A. de Vreeze; D de Jong; W Koops; P M. Nederlof; A Ariaens; R L. Haas; F van Coevorden |
| 77 | #39201 SMALL MOLECULE INHIBITORS OF EZRIN AS ANTI-METASTATIC AGENTS IN OSTEOSARCOMA G Bulut; K Chen; E Glasgow; S Hong; H Lee; J Toretsky; I Daar; C Khanna; A Uren |
| 78 | #39203 DOWNREGULATION OF MET AS A TARGET FOR THERAPY IN METASTATIC OSTEOSARCOMA L M Guenther; F Cecchi; A Giubellino; A Naumova; A T Deyrup; C Khanna; L J Helman; S Kim |
| 78 | #39207 LEIOMYOSARCOMA ARISING FROM THE PANCREATIC DUCT: A CASE REPORT AND REVIEW OF CURRENT LITERATURE ON PANCREATIC SARCOMAS N Marie DeMers Riddle, MD; B Quigley, MD; I Browarsky, MD |
| 78 | #39221 RECURRENCE PATTERNS AND SURVIVAL IN PATIENTS WITH INTERMEDIATE AND HIGH GRADE MYXOFIBROSARCOMA K E. Haglund; C P. Raut; A F. Nascimento; Q Wang; S George; E H. Baldini |
| 79 | #39222 CARBON ION RADIOTHERAPY FOR LOCALIZED PRIMARY SARCOMA OF THE EXTREMITIES S Sugahara; T Kamada; R Imai; H Tsuji; M Suzuki; T Okada; H Tsujii; S Tatezaki |
| 79 | #39230 ADJUVANT HIGH-DOSE-RATE BRACHYTHERAPY (HDRBT) FOR EXTREMITY SOFT TISSUE SARCOMAS: INITIAL CLINICAL EXPERIENCE D Wang; J Rownd; A X Li; D King; D Hackbarth |
| 79 | #39236 TELANGIECTATIC SOFT TISSUE SARCOMAS: A CLINICOPATHOLOGIC ANALYSIS OF AN UNUSUAL AGGRESSIVE FEATURE OF SOME HIGH-GRADE SARCOMAS: A NEWLY DESCRIBED AND RARE ENTITY ANALAGOUS TO ITS BONY COUNTERPART (TELANGIECTATIC OSTEOSARCOMA) A Sternheim; X Jin; B M Shmookler; J S Jelinek; M Miles Malawer |
| 80 | #39248 MEGAVOLTAGE-CT IMAGE GUIDANCE TO TREAT PARASPINAL SARCOMA: MARGIN REDUCTIONS AND ADAPTIVE RADIOTHERAPY K Kainz; X Allen Li; D Wang |
| 80 | #39249 PHOSPHOPROTEOMIC AND FUNCTIONAL GENOMIC SCREENING OF RECEPTOR TYROSINE KINASES IN OSTEOSARCOMA A N Rettew; P J Getty; E M Greenfi eld |
| 80 | #39257 CHONDROSARCOMA: SKIP METASTASES A Kevin Raymond; W Wang; N J. Hilliard; M J. Deavers; N Chen; V O. Lewis; J E. Madewell |
| 81 | #39260 PRIMARY SYNOVIAL SARCOMA OF DIGESTIVE SYSTEM: A CLINICOPATHOLOGIC AND MOLECULAR ANALYSIS OF 5 CASES S Romeo; F Canal; L Laurino; G Mazzoleni; M Montesco; L Valori; M Campo Dell' Orto; S Rossi; A Dei Tos |
| 81 | #39262 MULTIFOCAL EXTREMITY HEMANGIOENDOTHELIOMA TREATED WITH RADIOTHERAPY N Larrier; L Dodd; B Brigman |
| 81 | #39278 OSTEOSARCOMA OF THE EXTREMITY: RESULTS OF METHOTREXATE BASED VS NON-METHOTREXATE BASED COMBINATION CHEMOTHERAPY A Kawai; M Miyagi; K Kikuta; K Oshima; K Numoto; K Takeda; E Kobayashi; U Yamaguchi; H Chuman; Y Beppu; A Hosono; A Makimoto |
| 82 | #39284 CLINICAL RESULTS FROM THE NIH GIST CLINIC AND IDENTIFICATION OF SHD MUTATIONS S Kim; M Lodish; M Raygada; C Stratakis; A Pappo; C Antonescu; G Demetri; K Janeway; J Trent; M von Mehren; M LaQuaglia; P Gay; T McAleer; L Helman |
| 82 | #39287 BUB1B IS NECESSARY FOR GROWTH AND SURVIVAL OF PEDIATRIC SARCOMAS X Wan; C L Yeung; V N Ngo; S Kim; C Khanna; L M Staudt; L J Helman |
| 82 | #39289 SRC INHIBITION DECREASES THE PROLIFERATION OF HUMAN OSTEOSARCOMA CELLS IN VITRO AND TUMOR GROWTH IN VIVO H Li; X Wan; S Hong; C Khanna; M Stuart; L Helman; S Kim |
| 82 | #39295 WHAT IS THE INCIDENCE OF RADIATION INDUCED FRACTURES OF THE FEMUR FOLLOWING THE TREATMENT OF SOFT TISSUE SARCOMAS OF THE THIGH ? IS COMPARTMENTAL LOCALIZATION SIGNIFICANT ? ANALYSIS AND LONG TERM FOLLOW-UP OF 188 PATIENTS T Ben-Tov; T Pritsch; A Sternheim; J Bickels; M Miles Malawer |
| 83 | #39298 NANOPARTICLE- TARGETING INTEGRINS TO IMPROVE SURGICAL RESECTION OF PRIMARY TUMOR AND LUNG METASTASIS IN ADVANCED OSTEOSARCOMA A Dutour; V Josserand; J Coll; A Decouveleare; P Dumy; F Chotel; J Blay; R Rousseau |
| 83 | #39302 SIDE POPULATION CELLS HAVE THE CHARACTERISTICS OF CANCER STEM-LIKE CELLS/CANCER-INITIATING CELLS IN BONE SARCOMAS M Murase; M Kano; T Tsukahara; T Torigoe; S Kawaguchi; S Kimura; A Takahashi; Y Uchihashi; T Wada; T Kondo; N Sato; T Yamashita |
| 83 | #39304 CONE-BEAM CT GUIDANCE FOR SET-UP VERIFICATION IN EXTREMITY SOFT TISSUE SARCOMA PATIENTS A Betgen; R Haas; J Sonke |
| 84 | #39306 EFFECTIVENESS AND TOLERABILITY OF ADJUVANT TREATMENT IN PATIENTS WITH SOFT TISSUE SARCOMAS AND UNFAVORABLE PROGNOSTIC FACTORS. B Jacek Pilecki; J Strojek; A Kaminski; I Cedrych; A Wygoda; M Hutnik; M Golen; K Skladowski |
| 84 | #39330 RADIOTHERAPY AND EXTENT OF SURGICAL RESECTION IN RETROPERITONEAL SOFT-TISSUE SARCOMA: MULTI-INSTITUTIONAL ANALYSIS OF 292 PATIENTS S Sampath; T E. Schultheiss; Y J. Hitchcock; R Lor Randall; D C. Shrieve; J Y.C. Wong |
| 84 | #39340 EVALUATION OF OSTEOSARCOMA CELL BEHAVIOR AND METASTATIC POTENTIAL WITH THE USE OF A REPRODUCIBLE ORTHOTOPIC XENOGRAFT MODEL M T Iannolo; J A Horton; E R Fisher; M J. Allen; T A Damron |
| 85 | #39349 PHASE I TRIAL OF TWO SCHEDULES OF VINCRISTINE, ORAL IRINOTECAN, AND TEMOZOLOMIDE (VOIT REGIMEN) FOR CHILDREN WITH REFRACTORY SOLID TUMORS: A CHILDREN'S ONCOLOGY GROUP PHASE I CONSORTIUM STUDY L Wagner; J Perentesis; J Reid; M Ames; S Safgren; M Nelson; M Ingle; S Blaney; P Adamson |
| 85 | #39357 EFFICACY AND SAFETY OF TOPOTECAN AND CYCLOPHOSPHAMIDE COMBINATION FOR ADOLESCENTS AND YOUNG ADULT WITH REFRACTORY OR RELAPSED SMALL-ROUND CELL SARCOMA A Hosono; A Makimoto; Y Funakoshi; M Miyagi; K Kikuta; U Yamaguchi; K Chuman; Y Beppu; A Kawai |
| 85 | #39366 IMAGE-GUIDED ADAPTIVE RADIOTHERAPY FOR SOFT-TISSUE SARCOMAS INVOLVING NASAL/PARANASAL SINUS AND ORBIT: INITIAL CLINICAL EXPERIENCES K Kainz; D Wang |
| 86 | #39367 CYCLIN E IS FREQUENTLY AMPLIFIED IN OSTEOSARCOMA W Lockwood; D Stack; W Lam; J Squire; M J O'Sullivan |
| 86 | #39370 PHARMACOGENOMIC ASSOCIATION TO GASTROINTESTINAL TOXICITIES IN PATIENTS WITH HIGH RISK RHABDOMYOSARCOMA TREATED WITH VINCRISTINE AND IRINOTECAN B J. Weigel; E Lyden; M Tagen; D Hawkins; P Breitfeld; W Meyer; J Anderson; C Stewart |
| 86 | #39381 IMAGE GUIDED CORE NEEDLE BIOPSY AS THE FIRST-LINE MODALITY FOR THE PATHOLOGIC DIAGNOSIS OF SOFT TISSUE MASSES K Votanopoulos; J Chelnis; A Litwin; R Cheney; J M Kane III |
| 87 | #39387 PRELIMINARY REPORT: DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE (DCE-MRI) FOR ASSESSING INTRATUMORAL MICROVASCULAR CHANGES IN PATIENTS WITH HIGH GRADE SOFT TISSUE SARCOMA, TREATED WITH PREOPERATIVE RADIOTHERAPY Y J Hitchcock; M Schabel; D C Shrieve; B Salter |
| 87 | #39391 INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (IGF1R) IS HIGHLY EXPRESSED IN PEDIATRIC WILDTYPE GASTROINTESTINAL STROMAL TUMOR (GIST) K Anne Janeway; M J Zhu; J Barretina; G D Demetri; J A Fletcher |
| 87 | #39405 PEDIATRIC MUSCULOSKELETAL TUMORS - A REGISTRY DESCRIPTION IN THE PEDIATRIC SETTING OF BENIGN AND MALIGNANT TUMORS T Scharschmidt; J Lisle; D Hawkins; J Eary; E Conrad |
| 88 | #39411 DESMOPLASTIC SMALL ROUND CELL TUMOR: EVOLVING TREATMENT OPTIONS V Subbiah; P M Anderson; A Hayes-Jordan; A Taucer; J A Ludwig |
| 88 | #39413 THE ROLE OF FIBROBLAST GROWTH FACTORS IN EMBRYONAL RHABDOMYOSARCOMA PROGRESSION B Charbonneau; D Largaespada |
| 88 | #39414 SOFT TISSUE SARCOMAS OF THE HEAD AND NECK. ANALYSIS OF TREATMENT OUTCOME AND SURVIVAL. SINGLE INSTITUTION EXPERIENCE I Cedrych; B Pilecki; A Kaminski; J Strojek; M Hutnik; K Skladowski |
| 89 | #39420 RESISTANCE TO THE IGF-IR INHIBITION BY THE HUMAN MONOCLONAL ANTIBODY R1507 MAY BE MEDIATED BY EGFR IN OSTEOSARCOMA D Kamara; W Ellen Zhang; L Baker; R Gorlick; E Anders Kolb |
| 89 | #39427 EMOTIONAL ACCEPTANCE AND SATISFACTION FOLLOWING PEDIATRIC LIMB SALVAGE WITH A NON-INVASIVE EXPANDABLE ENDOPROSTHESIS Eric R. Henderson, German A. Marulanda, Andrew M. Pepper, Justin D. Millard, David Cheong, G. Douglas Letson |
| 89 | #39428 NON-INVASIVE VS. INVASIVE PEDIATRIC EXPANDABLE LIMB SALVAGE ? A COST ANALYSIS E R. Henderson; A M. Pepper; G A. Marulanda; J D. Millard; D Cheong; G Leston |
| 90 | #39442 TREATMENT OF NON-RESECTABLE OSTEOSARCOMA (OSA) WITH PROTON THERAPY (PT) I Frank Ciernik; A Niemierko; W Kobayashi; Y Chen; T Yock; D Ebb; D C. Harmon; E Choy; K A. Raskin; F J. Hornicek; T F. DeLaney |
| 90 | #39444 EXTRATHORACIC SOLITARY FIBROUS TUMOR: A RARE ENTITY WITH AN UNPREDICTABLE BEHAVIOUR E L Staals; E Palmerini; M Antonio Nogales; M Alberghini; M Gambarotti; S Ferrari; P Picci; M Mercuri |
| 90 | #39459 SARCOMA METASTASES INVOLVING THE SKIN W Wang; V G Prieto; D C Lev; A J F Lazar |
| 90 | #39463 AN OPPORTUNITY TO OPTIMIZE TRANSLATION OF MTOR INHIBITORS IN SARCOMA THROUGH A CONNECTION WITH THE UNFOLDED PROTEIN RESPONSE J Briggs; C Khanna |
| 91 | #39467 NOVEL CHROMOSOMAL TRANSLOCATION T(17;19(P13;Q13 IN UNDIFFERENTIATED SARCOMA M J O'Sullivan; D Stack; T Morris; P Sorensen |
| 91 | #39474 DEFINITIVE HIGH DOSE PROTON RADIOTHERAPY FOR UNRESECTED PARASPINAL CHORDOMAS Y Chen; W Kobayashi; F Hornicek; A Rosenberg; G P Nielsen; S Childs; T DeLaney |
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| 91 | #38489 MYOMA? OOPS? LEIOMYOSARCOMA! R Bernstein-Molho; V Soyfer; O Merimsky |
| 92 | #38623 THE FEMORAL NECK-LESSER TROCHANTERIC AXIS AS A LANDMARK FOR TUMOR ENDOPROSTHESIS PLACEMENT: AN IN VIVO STUDY A D. Uglialoro; K S. Beebe; J Benevenia; F R. Patterson |
| 92 | #39180 ATYPICAL MUSCLE TEAR PRESENTATIONS MAY MIMIC SOFT TISSUE SARCOMA R L. Slotcavage; R D. Lackman; C M. Ogilvie |
| 92 | #39181 APPROPRIATENESS OF RADIOLOGISTS MRI RECOMMENDATIONS FOR SOFT TISSUE TUMORS C M. Ogilvie; S A. Jorgensen |
| 92 | #39210 EMERGENCY CONDITIONS AMONG CHILDREN WITH VARIOUS TYPES OF SARCOMAS DURING LAST 3 MONTHS OF LIFE S Postovsky; B Moaed; R Ofi r; M Weyl Ben Arush |
| 93 | #39212 EVALUATION OF A NONINVASIVE EXPANDABLE PROSTHESIS IN MUSCULOSKELETAL ONCOLOGY PATIENTS FOR THE UPPER AND LOWER EXTREMITY A D. Uglialoro; N Patel; F R. Patterson; J Benevenia; K S. Beebe |
| 93 | #39213 THE EVALUATION OF A NEW MODULAR INTERCALARY DEVICE A D. Uglialoro; K S. Beebe; F R. Patterson; J Benevenia |
| 93 | #39224 OF MICE AND MEN: DIVERGENT RISKS OF TERIPARATIDE-INDUCED OSTEOSARCOMA V Subbiah; V Madsen; K Raymond; R S Benjamin; J A Ludwig |
| 93 | #39265 VACUUM ASSISTED WOUND CLOSURE FOR RADIOTHERAPY IN SARCOMAS N Larrier |
| 94 | #39274 RECONSTRUCTION FOLLOWING ONCOLOGIC RESECTION OF THE PROXIMAL HUMERUS AND ROTATOR CUFFF USING ALLOGRAFT BONE AND REVERSE TOTAL SHOULDER ARTHROPLASTY J L Jones; B E McGrath; M Tetro |
| 94 | #39297 COMPRESSIVE OSSEOINTEGRATION OF PROXIMAL FEMORAL ENDOPROSTHESES FOR MASSIVE ONCOLOGIC RECONSTRUCTION R Lisa Wustrack; R O'Donnell |
| 95 | #39315 HEMIPELVIC PROSTHETIC REPLACEMENT FOR PELVIC SARCOMA B Berrey |
| 95 | #39332 FEASIBILITY OF DIFFUSION WEIGHTED MR IMAGING FOR CHARACTERIZATION OF SOFT TISSUE TUMOURS: PRELIMINARY FINDINGS AND CORRELATION WITH HISTOLOGICAL PARAMETERS E Drakonaki; E de Bree; T Maris; E Giannikaki; J Melissas; A Karantanas |
| 95 | #39333 BISPHOSPHONATE INDUCED IMPENDING AND PATHOLOGIC BILATERAL SUBTROCHANTERIC FEMUR FRACTURES: A REPORT OF TWO CASES J Benevenia; H Goodman; A D Uglialoro; K S. Beebe; F R. Patterson |
| 95 | #39343 RECOGNITION OF EARLY STAGE CHONDROSARCOMAS OF THE DISTAL FEMUR: SMALL PAINFUL ECCENTRIC LESIONS INVOLVING THE CORTEX I Iofi n; R Mikael Henshaw |
| 96 | #39348 A CASE REPORT: APPENDICEAL ADENOCARCINOMA METASTATIC TO BONE I Iofi n; R Mikael Henshaw |
| 96 | #39355 DEDIFFERENTIATED RHABDOMYOSARCOMA WITHIN A PRIMARY EXTREMITY LIPOSARCOMA: MULTIDISCIPLINARY MANAGEMENT OF A 30CM TUMOR AND LITERATURE REVIEW. G W Dittrick; D Nugent; R J Gonzalez; D Cheong; G Douglas Letson |
| 96 | #39389 CLINICAL OUTCOME FOR PATIENTS WITH METASTATIC SOFT-TISSUE SARCOMA TREATED ON CLINICAL TRIALS K S Perlewitz; Y Chen; M L Holtorf; C W Ryan |
| 97 | #39424 A SARC GLOBAL COLLABORATIVE PHASE II TRIAL OF R1507, A RECOMBINANT HUMAN MONOCLONAL ANTIBODY TO THE INSULIN-LIKE GROWTH FACTOR-1 RECEPTOR (IGF1R) IN PATIENTS WITH RECURRENT OR REFRACTORY SARCOMAS. A Pappo; S Patel; J Crowley; D Reinke; R Maki; C Brownstein; S Ritland; S Chawla; A Staddon; G Vassal; L Helman |
| 97 | #39426 FUNCTIONAL OUTCOMES FOLLOWING PEDIATRIC LIMB SALVAGE WITH A NON-INVASIVE EXPANDABLE ENDOPROSTHESIS E R. Henderson; A M. Pepper; G A. Marulanda; D Cheong; G Letson |
| 97 | #39429 A NEW CLASSIFICATION OF MEGAPROSTHESIS REVISION ? AN INDICATION- AND TREATMENT-ORIENTED SYSTEM E R. Henderson; B White; J Groundland; G A. Marulanda; D Cheong; H Temple; P Ruggieri; G Letson |
| 98 | #39430 GAIT EXAMINATION AFTER PELVIC SARCOMA RESECTION AND ALLOGRAFT RECONSTRUCTION E Y. Cheng |
| 98 | #39431 PERI-OPERATIVE EXPECTATIONS WITH REVISION OF LOWER EXTREMTIY SEGMENTAL MEGAPROSTHESIS FOR TUMOR E R. Henderson; G A. Marulanda; B White; J Groundland; D Cheong; P Ruggieri; H Temple; G Letson |
| 98 | #39436 SYNCHRONOUS PRIMARY EXTRASKELETAL OSTEOSARCOMA, FIBROMYXOID SARCOMA, AND GASTROINTESTINAL STROMAL TUMOR IN A PATIENT WITH WILD-TYPE P53 GENOTYPE Robert J. Canter, Robert M. Tamurian, Donna Walgenbach, David T. Cooke, Dariusz Borys |
| 99 | #39439 SACROILIAC PERCUTANEOUS SCREW STABILIZATION IN ONCOLOGIC PATIENTS WITH SACRAL INSUFFICIENCY FRACTURES O Binitie; F Vrionis; D Cheong |
| 99 | #39440 A NOVEL SURGICAL APPROACH FOR RESECTION OF ADDUCTOR COMPARTMENT SOFT TISSUE SARCOMAS OF THE THIGH O Binitie; R Gonzalez; G Douglas Letson; D Cheong |
| 99 | #39447 CONGENITAL INFANTILE FIBROSARCOMA OF THE ORBIT A Podda; F Cristina; J Goldberg; O Alvarez; J Davis; M Andreansky; J Reichbach; N Lewis; E White; T Hustache; J Barredo |
| 99 | #39460 AGE AS A PROGNOSTIC FACTOR IN PATIENTS WITH STS J Strojek; A Kaminski; B Pilecki; I Cedrych; Z Kolosza |
| 100 | #39466 NEW INDICATIONS FOR THE USE OF CUTTING STAPLERS IN ORTHOPAEDIC ONCOLOGY G Marulanda; J Dave; E Henderson; D Cheong; D Letson |
| 100 | #39468 THE USE OF A BIPOLAR SEALER DEVICE TO ACHIEVE HEMOSTASIS IN ORTHOPAEDIC ONCOLOGY G Marulanda; D Johnson; E Henderson; D Cheong; D Letson |
| 100 | #39469 MULTICENTER COMPARISON OF HEMOSTASIS DUE TO TRANSCOLLATION G Marulanda; E Henderson; D Cheong; M Mont; D Letson |
| 101 | #39470 NOVEL TECHNIQUE OF LARGE MUSCULOSKELETAL SARCOMAS RESECTION WITH THE USE OF A CUTTING STAPLER AND A BIPOLAR SEALER DEVICE G Marulanda; T Born; E Henderson; D Cheong; D Letson |
| 101 | #39472 NON INVASIVE EXTENDABLE PROSTHESES: REPORT ON THE ONLY COHORT OF AMERICAN PATIENTS G Marulanda; E Henderson; D Cheong; D Letson |