Thursday, November 13, 2008

07:00  -  08:00
Ballroom Hall

Registration and Poster Set-Up

08:00  -  12:00
Ballroom

SARC Meeting

09:00  -  12:00
Landmark 2 & 3

Nurses and Allied Health Professionals Meeting

11

#34981 MAGNETIC RESONANCE SIMULATION (SMR) FOR LOWER EXTREMITY SOFT TISSUE SARCOMA (LE-STS) PATIENTS TREATED WITH PRE-OPERATIVE
INTENSITY MODULATED RADIATION THERAPY (IMRT)
Colleen I Dickie-Euler, Amy L Parent; Anthony M Griffi n; Anna K Kirilova; Peter W.M. Chung; Michael B Sharpe; Jay Wunder; Peter Ferguson; Charles N Catton; Brian O’Sullivan

11

#35042 A RETROSPECTIVE STUDY COMPARING INITIAL GP DATA ON TWO WEEK WAIT REFERRALS WITH CLINICAL REVIEW AND IMAGING AT A SPECIALIST CENTRE
Lin Russell; Luan Suckling

11

#35081 COLLABORATIVE MANAGEMENT OF SARCOMA PATIENTS IN 2008: INTEGRATING IMPROVEMENTS IN CARE FROM NOVEL THERAPIES TO DEVELOPMENT OF NEW RESOURCES
Amy S Potter; Suzanne George; George Demetri; Andrew Wagner; Jeffrey A Morgan; Melissa Hohos; Bonnie Dirr; James Butrynski; Tarsha Colon; Kathleen Polson

11

#35090 CARE OF THE INTERNATIONAL PEDIATRIC PATIENT AND FAMILY - THE PUERTO RICO PATIENT ASSISTANCE PROGRAM
Sara Swaim, RN; Amy Federico, PNP; Annette Werger, PNP; Holcombe Grier, MD; Mark Gebhardt, MD; Allen Goorin, MD

12

#35092 EXAMINING ONE SARCOMA CENTER’S EXPERIENCE WITH SUCCESSFUL RECRUITMENT TO RANDOMIZED, PLACEBO CONTROLLED CLINICAL TRIALS
Melissa Hohos; Amy S. Potter; Kathleen Polson; George Demetri; Jeffrey A. Morgan; Andrew J. Wagner; Bonnie Dirr; Tarsha Colon; James Butrynski; Serena Wong; Margaret O’Mara; Suzanne
George

09:00  -  12:00

Patient Advocacy Groups Meeting

13:30  -  13:40
Ballroom

Introduction to 14th Annual Meeting

13:40  -  14:30
Ballroom

Molecular Pathology of Sarcomas
Session Chairs: Andrea Deyrup, Paolo dei Tos

12

#34879 PROGNOSTIC VALUE OF MYOGENIC DIFFERENTIATION IN ADULT SOFT TISSUE SARCOMAS. A STUDY OF 855 CASES FROM THE FRENCH SARCOMA
GROUP
Nathalie Stock; Marie Christine Chateau; Francoise Collin; Louis Guillou; Agnes Leroux; Bernard Marques; Jean Jacques Michels; Dominique Ranchère; Yves Marie Robin; Philippe Terrier; Martine Trassard; Isabelle Valo; Jean Michel Coindre

12

#34956 GENE EXPRESSION PROFILE OF POORLY DIFFERENTIATED SYNOVIAL SARCOMA
Robert Nakayama; Tadashi Ichikawa; Tadashi Hasegawa; Akira Kawai; Akira Ogose; Teruhiko Yoshida; Hideo Morioka; Hiroo Yabe; Yoshiaki Toyama

13

#35080 GROWTH FACTORS AND PATHWAY ACTIVATION IN CHORDOMA
Carolyn J. Hoban; Dafydd G. Thomas; David R. Lucas; Laurence H. Baker

13

#35032 RECURRENT CHROMOSOMAL COPY NUMBER ALTERATIONS IN CHORDOMA
G. Petur Nielsen; Vikram Deshpande; Andrew Rosenberg; Julie Miller; John Iafrate; Francis Hornicek

14:30  -  15:30
Ballroom

Gynecological Sarcomas
Session Chairs: Beatrice Seddon (to give introductory talk), Martee Hensley

13

#34982 STAGE SPECIFIC OUTCOMES OF PATIENTS WITH UTERINE LEIOMYOSARCOMA: A COMPARISON OF FIGO AND AJCC STAGING SYSTEMS
Oliver Zivanovic; Mario M. Leitao; Alexia Iasonos; Qin Zhou; Robert A. Soslow; Margrit M. Juretzka; Dennis S. Chi; Richard R. Barakat; Murray F. Brennan; Martee L. Hensley

14

#34970 PREDICTIVE VALUE OF FIGO AND AJCC STAGING SYSTEMS IN 230 PATIENTS (PTS) WITH UTERINE LEIOMYOSARCOMA (ULMS): IS IT TIME FOR A
CHANGE?
Chandrajit P Raut; Marisa R Nucci; Qian Wang; Judith Manola; Michelle Ouellette; Kathleen M Polson; Amy S Potter; Monica M Bertagnolli; Michael G Muto; Elizabeth H Baldini; James E Butrynski; George D Demetri; Jeffrey A Morgan; Andrew J Wagner; Christopher D M Fletcher; Suzanne George

14

#34855 WILMS’ TUMOR GENE 1 (WT1) IS A NEW PROGNOSTIC MARKER IN HIGH GRADE UTERINE SARCOMA
An Coosemans; Ben Van Calster; Stefaan W Van Gool; Ignace Vergote; Frédéric Amant

15

#34961 ADJUVANT GEMCITABINE PLUS DOCETAXEL FOR COMPLETELY RESECTED STAGE I-IV HIGH GRADE UTERINE LEIOMYOSARCOMA: RESULTS OF A PHASE II TRIAL
Martee L Hensley; Nicole Ishill; Robert Soslow; Nadeem Abu-Rustum; Paul Sabbatini; Jason Konner; William Tew; David Spriggs; Carol Aghajanian

15:30  -  16:15
Ballroom Hall

Tea and Poster Viewing

16:15  -  16:30
Ballroom Hall

Poster Discussion 1
Session Chair: Brian O’Sullivan
34806, 34812, 34813, 34818, 34830, 34841, 34853, 34872, 34873, 34887, 34892, 34905, 34916, 34920, 34933, 34941, 34943, 34944, 34949, 34950, 34953, 34966, 34979, 34985, 34992, 34994, 34998, 34999, 35002, 35003, 35004, 35009, 35023, 35025, 35027, 35028, 35045, 35048, 35054, 35062, 35065, 35078, 35084, 35088, 35093, 35109, 35110, 35114, 35118, 35120, 35126, 35135, 35138, 35141, 35142, 35155, 35157, 35158, 35171

16:30  -  18:00
Ballroom

Fibromatosis: Biology & Multidisciplinary Management
Session Chair: Dina Lev (to give introductory talk), Andrew Hayes

15

#34875 ALTERNATIVE CLINICAL APPROACH IN AGGRESSIVE FIBROMATOSIS: WAIT & SEE FRONTLINE POLICY. A MULTI-INSTITUTIONAL RETROSPECTIVE REVIEW
Marco Fiore; Annalisa Perego; Elisabetta Pennacchioli; Paola Collini; Palma Dileo; Silvia Stacchiotti; Axel Le Cesne; Paolo Giovanni Casali; Alessandro Gronchi; Sylvie Bonvalot

16

#35006 DESMOID TUMOURS: TO OPERATE OR NOT TO OPERATE
Rafi q H Abed; Adesegun Abudu; Simon Carter; Rob Grimer; Roger Tillman; Lee Jeys

16

#34885 THE DESMOID TUMOR PROTEOME; IDENTIFYING MOLECULAR MARKERS USING A CLINICALLY ANNOTATED TISSUE MICROARRAY
Shohrae Hajibashi; Wei-Lien Wang; Alexander J.F. Lazar; Daniel Tuvin; Carla L. Warneke; Dolores Lopez-Terrada; Raphael E. Pollock; Dina Lev

16

#35119 MESENCHYMAL PROGENITOR CELLS ARE INVOLVED IN THE FORMATION OF AGGRESSIVE FIBROMATOSIS (DESMOID TUMOR)
Colleen Wu; Benjamin A Alman

17

#34904 MULTIMODALITY TREATMENT OF MESENTERIC DESMOID TUMORS
Monica M Bertagnolli; Jeffrey A Morgan; Christopher DM Fletcher; Chandrajit P Raut; Palma Dileo; Ritu R Gill; George D Demetri; Suzanne George

17

#35057 ACTIVITY OF MEDICAL THERAPY (METHOTREXATE + VINBLASTINE/ VINORELBINE OR TAMOXIFEN) IN DESMOID FIBROMATOSIS (DF): RETROSPECTIVE ANALYSIS OF 79 PATIENTS FROM A SINGLE INSTITUTION
Palma Dileo; Claudio Piovesan; Marianna Silletta; Elisa Puma; Roberta Sanfi lippo; Elisabetta Pennacchioli; Marco Fiore; Alessandro Gronchi; Paolo Casali

17

#34852 SUCCESSFUL TREATMENT OF FIBROMATOSIS WITH HYDROXYUREA: ANALYSIS OF 20 PEDIATRIC CASES
Naomi J Balamuth; Richard B Womer

Friday, November 14, 2008

07:00  -  08:00
Champagne Room

Executive Committee Meeting

08:00  -  09:00
Ballroom

Surgery
Session Chair: Alessandro Gronchi, Lor Randall

36

#34880 MORBIDITY OF AN UNPLANNED EXCISION OF SOFT TISSUE SARCOMAS: A QUANTITATIVE ASSESSMENT
Robert M Tamurian, MD; Robert A. Zlotecki, MD PhD; Zachary B Adler, MD; Mark T Scarborough; C. Parker Gibbs, MD

37

#34876 MARGINAL SURGERY IN PRIMARY EXTREMITY SOFT TISSUE SARCOMA: PROGNOSTIC ROLE OF ANATOMIC BARRIER AT CLOSEST SURGICAL MARGIN
Marco Fiore; Marzia Riccardo; Elisabetta Pennacchioli; Paola Collini; Laura Lozza; Alessandro Cadeo; Paolo Casali; Alessandro Gronchi

37

#34869 CLINICAL VARIABLES, PATHOLOGICAL FACTORS, AND MOLECULAR MARKERS FOR ENHANCED SOFT TISSUE SARCOMA PROGNOSTICATION
Guy Lahat; Wang Wei-lien; Daniel Tuvin; Daniel A Anaya; Caimiao Wei; Nabiyu Bekele; Kerrington D Smith; Alexander J Lazar; Peter W Pisters; Raphael E Pollock; Dina Lev

38

#35066 PROGNOSTIC FACTORS FOR LONG-TERM SURVIVAL AFTER PULMONARY METASTASECTOMY IN SARCOMA PATIENTS: A 16 -YEAR EXPERIENCE
Simon Jordan; Peter Goldstraw; Elizabeth Belcher; Ambrus Szánthó; Jeremy Whelan; Beatrice Seddon; Maria Michelagnoli; Anna Cassoni; Sandra Strauss; Michelle Scurr; Frank Saran; Ian
Judson; George Ladas

38

#34860 ROLE OF SENTINEL LYMPH NODE BIOPSY IN THE STAGING OF SYNOVIAL, EPITHELIOID, AND CLEAR CELL SARCOMAS
Ugwuji Maduekwe; Francis J. Hornicek; Mark J. Ott; Dempsey S. Springfi eld; Kevin A. Raskin; Edwin Choy; David C. Harmon; Andrew E. Rosenberg; G. Petur Nielsen; Thomas F. DeLaney;
Sam S. Yoon

09:00  -  10:00
Ballroom

Bone Sarcomas 1- Pediatric Oncology
Session Chair: Paul Meyers, Herbert Jurgens

38

#34849 THE MORE IT HURTS, THE BETTER IT WORKS? CHEMOTHERAPY TOXICITY AS A PREDICTOR OF OUTCOME FROM OSTEOSARCOMA: A REPORT FROM THE EUROPEAN OSTEOSARCOMA INTERGROUP
Anne McTiernan; Rachel C Morgan; Matthew R Sydes; Barbara Uscinska; Martine Van Glabbeke; Vivien Bramwell; Robert L Souhami; Ian Lewis; Antonie H Taminiau; Marianne A Nooij; Pancras C. Hogendoorn; Jeremy S Whelan

39

#35051 CHANGE IN ANATOMIC DISTRIBUTION OF RELAPSES WITH ACCELERATED CHEMOTHERAPY IN EWING SARCOMA
Richard B Womer; Daniel C West; Mark D Krailo; Paul S Dickman; Bruce Pawel

39

#35047 THE VALUE OF LOCAL TREATMENT IN PATIENTS WITH EXTRAPULMONARY METASTAZISED EWING TUMORS (EPMET)
Uta Dirksen; Julia Häusler; Tobias Bölling; Andreas Ranft; Georg Gosheger; Volker Vieth; Heribert Jürgens

39

#35094 ACTIVITY OF SCH 717454 IN SUBJECTS WITH RELAPSED OSTEOSARCOMA OR EWING’S SARCOMA (STUDY P04720)
Peter Anderson; Keith Skubitz; Robin Miller; William Meyer; Brian Lu

40

#34973 ADDITION OF PAMIDRONATE TO CHEMOTHERAPY FOR TREATMENT OF OSTEOSARCOMA (OS) IS FEASIBLE
Paul A. Meyers; John H. Healey; Edward Athanasian; Patrick Boland; Carol Morris; Michael P. Laquaglia; Cristina Antonescu; Leonard Wexler; Pamela Merola; Alexander Chou; Sara Abramson; Michael Kellick

10:00  -  10:30
Ballroom Hall &
Music Room

Coffee Break & Poster Viewing

10:30  -  11:45
Ballroom

NF1: MPNST and Other Sarcomas, Diagnosis & Treatment
Session Chair: Ros Ferner (introductory talk), Dave Viskochil

40

#35059 18FDG PET/CT IN THE DIAGNOSIS OF MALIGNANT PERIPHERAL NERVE SHEATH TUMOURS
Victoria S Warbey; Rosalie E Ferner; Michael J O’Doherty

40

#35152 GENETIC ANALYSIS OF PERIPHERAL NERVE SHEATH TUMOURS IN NF1 PATIENTS
Eline Beert; Bruno Daniels; Hilde Brems; Ivo De Wever; Frank Van Calenbergh; Patrick Schöffski; Maria Debiec-Richter; Raf Sciot; Eric Legius

41

#34868 MALIGNANT PERIPHERAL NERVE SHEATH TUMORS (MPNST): CLINICAL, PATHOLOGIC AND MOLECULAR PREDICTORS OF SURVIVAL
Kerrington David Smith; Chang-ye Zou; Jun Liu; Guy Lahat; Alex JF Lazar; Raphael E Pollock; Dina Lev

41

#35055 MICROARRAY GENE EXPRESSION DATA UTILIZED TO IDENTIFY PUTATIVE SERUM BIOMARKERS OF NEUROFIBROMATOSIS TYPE 1 ASSOCIATED TUMORS
Trent Hummel; Yonatan Mahler; Shyra Miller; Walter Jessen; Bruce Aronow; Timothy Cripe; Nancy Ratner

41

#35072 GASTROINTESTINAL STROMAL TUMOR (GIST) IN NEUROFIBROMATOSIS 1 (NF1) PATIENTS: A CLINICOPATHOLOGIC ANALYSIS OF NINE CASES
Elena Fumagalli; Paola Coco; Elena Palassini; Palma Dileo; Rossella Bertulli; Paolo G. Casali

41

#34974 NUCLEAR TP53 EXPRESSION IN MALIGNANT PERIPHERAL NERVE SHEATH TUMOURS IS AN INDEPENDENT MARKER OF POOR SURVIVAL
Helge R. Brekke; Matthias Kolberg; Rolf I. Skotheim; Kirsten Sundby Hall; Bodil Bjerkehagen; Bjorn Risberg; Henryk A. Domanski; Nils Mandahl; Sigbjørn Smeland; Håvard E. Danielsen; Fredrik Mertens; Ragnhild A. Lothe

11:45  -  12:45
Ballroom

Herman Suit Lecture – Professor Ivan Stamenkovic, Lausanne
“The Role of Mesenchymal Stem Cells in the Pathogenesis of Sarcomas”

12:45  -  14:00
Champagne Room

Board of Directors Meeting

14:00  -  15:00
Ballroom

Radiation Oncology
Session Chairs: Martin Robinson, Thomas DeLaney

42

#35069 ADEQUATE 3D TREATMENT VOLUME IN PREOPERATIVE RADIOTHERAPY IN EXTREMITY SOFT TISSUE SARCOMA
BoKyong Kim; Yen-Lin E Chen; David G Kirsch; Wendy K Kobayashi; Saveli I Goldberg; John A Wolfgang; Kevin A Raskin; Dempsey S Springfi eld; Joseph H Schwab; Sam S Yoon; Francis J Hornicek; Thomas F DeLaney

42

#35029 HYPOXIA IN RESECTABLE SOFT-TISSUE SARCOMAS ON FUNCTIONAL IMAGING WITH [18F]-FLUOROAZOMYCIN ARABINOSIDE POSITRON EMISSION TOMOGRAPHY POWERFULLY PREDICTS POOR RESPONSE TO RADIOTHERAPY AND EARLY RELAPSE
Kenneth Khamly; Peter Choong; Samuel Ngan; Rodney Hicks; Guy Toner; Jayesh Desai; Dianne Saward; David Thomas

43

#35012 CARBON ION RADIOTHERAPY FOR SACRAL CHORDOMA
Tadashi kamada; Reiko Imai; Hiroshi Tsuji; Itsuko Serizawa; Toru Okada

43

#35038 LONG-TERM FOLLOW-UP OF A PROSPECTIVE TRIAL OF PRE-OPERATIVE EXTERNAL-BEAM RADIATION AND POST-OPERATIVE BRACHYTHERAPY FOR RETROPERITONEAL SARCOMA
Lynn A. Mikula; Paul F. Ridgway; Charles N. Catton; Julia J. Jones; Brian O’Sullivan; Michael A. Ko; Carol J. Swallow

43

#34907 EFFECTIVENESS OF RADIOTHERAPY IN MYXOID SARCOMAS IS ASSOCIATED WITH A DENSE VASCULAR PATTERN
Ronald S.A. de Vreeze; Daphne de Jong; Rick L. Haas; Fiona Stewart; Frits van Coevorden

15:00  -  16:00
Ballroom

Biology 1 - Molecular Biology of Sarcomas
Session Chairs: Richard Gorlick, Jean-Michel Coindre

44

#35046 MULTIFOCAL MYXOID LIPOSARCOMA; METASTASIS OR SECOND PRIMARY? A MOLECULAR BIOLOGICAL ANALYSIS.
Ronald S.A. de Vreeze; Daphne de Jong; Petra M. Nederlof; Rick L. Haas; Frits van Coevorden

44

#35068 HUMAN MONOCLONAL ANTIBODY R1507 INHIBITS GROWTH OF OSTEOSARCOMA XENOGRAFTS AND IS EFFECTIVE IN COMBINATION WITH RAPAMYCIN
Edward Anders Kolb; Davida Kamara; Pooja Gidwani; Wengdong Ellen Zhang; Laurence H Baker; Richard G Gorlick

44

#34955 EWS/FLI REGULATES NKX2.2 VIA GLI IN A NON-SHH-DEPENDENT MANNER
Savita Sankar; Leah A. Owen; Stephen L. Lessnick

45

#35143 GLI2 AND P53 COOPERATE TO REGULATE IGFBP-3 MEDIATED CHONDROCYTE APOPTOSIS IN THE PROGRESSION FROM BENIGN TO MALIGNANT CARTILAGE TUMOURS Louisa Ho; Aneta Stojanovski; Heather Whetstone; Qingxia Wei; Elaine Mau Elaine Mau; Benjamin Alman; Jay Wunder

45

#35037 OSTEOCHONDROMAGENESIS: SOMATIC LOSS OF HETEROZYGOSITY MODELED VIA CRE-MEDIATED INVERSION OF THE SECOND EXON OF EXT1 IN CHONDROCYTES
Kevin B. Jones; Charles Searby; Gail Kurriger; Peter Roughley; Jose A. Morcuende; Joseph A. Buckwalter; Val C. Sheffi eld

16:00  -  16:45
Ballroom Hall

Afternoon Break & Poster Viewing

16:45  -  17:00
Ballroom Hall &
Music Room

            49

Poster Session 2
Session Chair: Robert Grimer

34593, 34800, 34807, 34819, 34825, 34827, 34839, 34840, 34859, 34861, 34864, 34867, 34913, 34934, 34939, 34942, 34949, 34951, 34967, 34969, 34986, 34988, 34993, 34995, 35013, 35026, 35030, 35031, 35035, 35039, 35063, 35074, 35083, 35087, 35089, 35091, 35098, 35099, 35100, 35101, 35103, 35105, 35107, 35108, 35111, 35112, 35125, 35128, 35134, 35137, 35139, 35148, 35160

17:00  -  17:30
Ballroom

45

THE SARC CAREER DEVELOPMENT AWARD
Laurence H Baker; Jennifer E Keene

17:00  -  17:30
Ballroom

Young Investigator Award Lectures
Session Chair: Laurence H Baker

46

#35020 SOFT TISSUE SARCOMA (STS) OF THE EXTREMITY - COMPARISON OF CONFORMAL POST-OPERATIVE RADIOTHERAPY (CRT) AND INTENSITY MODULATED RADIOTHERAPY (IMRT)
Young K Lee; Alexandra J Stewart; Frank H Saran

46

#34891 PFETIN AS A PROGNOSTIC BIOMARKER OF GASTROINTESTINAL STROMAL TUMORS REVEALED BY PROTEOMICS
Yoshiyuki Suehara; Kazutaka Kikuta; Kunihiko Seki; Tadashi Hasegawa; Kiyonaga Fujii;

17:30  -  18:00
Ballroom

Members Business Meeting

Saturday, November 15, 2008

08:00  -  09:00
Ballroom

Medical Oncology
Session Chairs: Shreyas Patel, Jeremy Whelan

65

#35064 COMBINATION THERAPY WITH TEMOZOLOMIDE AND BEVACIZUMAB (TMZ/BV) IN THE TREATMENT OF EMANGIOPERICYTOMA/SOLITARY FIBROUS TUMOR (HPC/SFT): AN UPDATED ANALYSIS.
Min S Park; Alexander J Lazar; Jonathan C Trent; Charles A Conrad; Joseph A Ludwig; Wei-Lien Wang; Piyaporn Boonsirikamchai; Haesun Choi; Shreyaskumar R Patel; Robert S Benjamin; Dejka M Araujo

65

#34936 ACTIVITY OF THE VEGFR/KIT TYROSINE KINASE INHIBITOR CEDIRANIB (AZD2171) IN ALVEOLAR SOFT PART SARCOMA.
Katherine Gardner; Michael Leahy; Manuel Alvarez-Gutierrez; Ian Judson; Michelle Scurr

65

#35024 ADVANCED CHORDOMA FOLLOWING IMATINIB (IM) RESISTANCE
Silvia Stacchiotti; Elena Tamborini; Andrea Marrari; Emanuela Virdis; Antonella Messina; Carlo Morosi; Flavio Crippa; Alessandro Gronchi; Silvana Pilotti; Paolo Casali

65

#35085 RESPONSES TO THE MTOR INHIBITOR SIROLIMUS IN PATIENTS WITH MALIGNANT PECOMA: REPORT OF THREE CASES
Andrew J. Wagner; Robert Maki; Cristina R. Antonescu; Christopher D. M. Fletcher; Jeffrey A. Morgan

66

#35067 A PHASE II STUDY OF INTRAVENOUS REOLYSIN (WILD TYPE REOVIRUS) IN THE TREATMENT OF PATIENTS WITH BONE AND SOFT TISSUE SARCOMAS METASTATIC TO THE LUNG
Monica Mita; Kamalesh Sankhala; Alain Mita; John Sarantopoulos; Anthony Carmona; Sanjay Goel; Rashmi Chugh; Scott Okuno; Matt Coffey; George Gill; Karl Mettinger

09:00  -  09:30
Ballroom

Diagnostic Techniques
Session Chairs: [Cyril Fisher], [Haesun Choi]

66

#34828 PERCUTANEOUS CT-GUIDED BIOPSY OF THE MUSCOLO-SKELETAL SYSTEM: RESULTS OF 1722 CASES
Eugenio Rimondi; Pietro Ruggieri; Giuseppe Bosco; Giuseppe Ussia; Teresa Calabrò; Andrea Angelini; Giuseppe Rossi; Ugo Albisinni

66

#35076 CORE NEEDLE BIOPSY IS HIGHLY ACCURATE IN DIAGNOSING BONE AND SOFT-TISSUE TUMOURS
Piya Kiatisevi; Torsten Nielsen; Malcolm Hayes; Peter L Munk; Amy E LaFrance; Paul W Clarkson; Bassam A Masri

67

#35016 PRELIMINARY EXPERIENCE USING PET-CT IN SUSPECTED PEDIATRIC BONE AND SOFT TISSUE SARCOMAS
Angela T Byrne; Michael Weber; Cristof Senger; Rod Rassekh; Ken L B Brown; Helen R Nadel

09:30  -  10:30
Ballroom

Bone Sarcomas 2 - Surgery and Molecular Biology
Session Chairs: Jay Wunder, Stephen Cannon

67

#34854 FREE VASCULARIZED FIBULAR GRAFTING FOR MALIGNANT BONE AND SOFT TISSUE TUMOR: RADIOLOGICAL, CLINICAL AND FUNCTIONAL OUTCOME
Mitsunori Kaya; Takuro Wada; Sataoshi Nagoya; Mikito Sasaki; Tadaki Matsumura; Toshihiko Yamashita

67

#34914 COMPLIANT FIXATION OF MEGA-NDOPROSTHETICS: RESULTS OF VARIED APPLICATIONS
Judd E. Cummings; Russell A. Ward; R. Lor Randall

68

#35000 LENTIVIRAL SHRNA SCREEN OF HUMAN KINASES IDENTIFIES NEW REGULATORS OF OSTEOSARCOMA CELL SURVIVAL AND APOPTOSIS
Zhenfeng Duan; Diana Ji; Edward Weinstein; Cao Yang; Edwin Choy; Henry Mankin; Francis Hornicek

68

#35116 A NOVEL PROFILING STRATEGY IN OSTEOSARCOMA IDENTIFIES EBF2 AS A MEDIATOR OF OPG INHIBITION TO TRAIL-INDUCED APOPTOSIS
Ana Patiño-García; Marta Zalacaín; Luis Sierrasesúmaga; Mikel San Julián; Cecilia Folio; Iker Antón; Diego Luis-Ravelo; Carolina Zandueta; Javier De Las Rivas; Gemma Toledo; Fernando Lecanda

68

#35140 NEW SURGICAL TECHNIQUE TO REDUCE DISLOCATIONS OF PROXIMAL AND TOTAL HUMERUS REPLACEMENTS AFTER TUMOR RESECTION
German Marulanda; Eric Henderson; Nazeem Virani; Dave Cheong; G. Douglas Letson

10:30  -  11:00
Ballroom Hall

Coffee Break & Poster Viewing

11:00  -  12:00
Ballroom

Nina Axelrad Lecture – Paul Myers – Memorial Sloan Kettering Cancer Center
“Development of a New Drug: Lessons from clinical trials”

13:30  -  14:30
Ballroom

Biology 2 - New Targets - Molecular Biology & Therapy
Session Chair: Lee Helman, Ian Johnson

69

#35145 COMBINATION PI3K/MTOR INHIBITION LIMITS CHORDOMA PROLIFERATION
Joseph H Schwab; Cristina Antonescu; John Healey; Patrick J Boland; Francis Hornicek; Zhenfeng Duan

69

#35008 THE PROTEOLYTIC MACHINERY AS NOVEL THERAPEUTIC TARGET IN GASTROINTESTINAL STROMAL TUMORS (GISTS)
Ying Liu; Joshua Parry; Anna Chin; Payel Chatterjee; Anette Duensing

69

#34962 EGR1 MEDIATES HISTONE DEACETYLASE SENSITIVITY IN SYNOVIAL SARCOMA VIA THE PTEN TUMOR SUPPRESSOR
Le Su; T. Michael Underhill; Torsten O. Nielsen

70

#34884 THE C-MET RECEPTOR CONTRIBUTES TO MOTILITY AND INVASION IN A BROAD RANGE OF STS HISTOLOGIES; A POTENTIAL ANTI-STS THERAPEUTIC TARGET
Sarah E Myers; Theresa G Nguyen; Quan S Zhu; Alex JF Lazar; Raphael Pollock; Dina Lev

70

#35041 OVERCOMING RESISTANCE TO CONVENTIONAL DRUGS IN EWING’ S SARCOMA AND IDENTIFICATION OF MOLECULAR PREDICTORS OF OUTCOME
Katia Scotlandi; Gastone Castellani; Daniel Remondini; Maria Cristina Manara; Massimo Serra; Sakari Knuutila; Piero Picci

14:30  -  15:30
Ballroom

Sarcoma Cooperative Trials Groups Overview
Session Chair: Jean-Yves Blay

15:30  -  16:15
Ballroom Hall &
Music Room

Afternoon Break and Poster Viewing

16:15  -  16:30
Ballroom

Poster Discussion 3
Session Chair: Robert Maki

34545, 34820, 34824, 34844, 34845, 34850, 34863, 34866, 34896, 34897, 34898, 34899, 34906, 34908, 34911, 34938, 34946, 34948, 34952, 34960, 34963, 34965, 34971, 34977, 34980, 34991, 35001, 35005, 35010, 35011, 35017, 35018, 35019, 35021, 35022, 35033, 35034, 35036, 35040, 35044, 35049, 35052, 35060, 35070, 35079, 35082, 35095, 35104, 35113, 35127, 35129, 35130, 35131, 35132, 35133, 35136, 35144, 35154, 35162, 35170