2002 CTOS
Annual Meeting Oral Presentations — Surgery
LOW
COMPLICATION RATE WITH LIMB-SPARING RESECTION AND ENDOPROSTHETIC
RECONSTRUCTION: SURVIVAL ANALYSIS OF 251 PATIENTS AND ANALYSIS OF
20-YEAR EXPERIENCE
[Abstract
ID: 59]
Category:
Surgery
Presentation:
Oral
Authors:
Felasfa M Wodajo1, Kristen Kellar-Graney1,
James C Wittig1, Robert M Henshaw1, Martin
M Malawer1
Author Institutions:
1Washington Cancer Institute, DC, United States
Presenter:
Felasfa M Wodajo
felasfa@earthlinl.net
Correspondent:
Felasfa M Wodajo
felasfa@earthlinl.net
Washington DC United States 20010
Ph: 202-877-3970
Fax: 202-877-8959
Objectives: In
order to evaluate patterns of complications and prosthetic survival
after endoprosthetic reconstruction for bone tumors, the authors
reviewed all procedures performed over a 20-year period at a single
institution.
Methods:
Patients who underwent one or more procedures with a segmental endoprosthesis,
except for saddle prostheses, are reported. Prosthetic failure is
defined as removal of a cemented component. Kaplan-Meier survival
analysis, interval to complication and the number of operations
per patient are calculated.
Results: A total of 251 patients underwent surgery. Of these,
197 patients (78%) underwent only one surgery. The remaining 54
underwent a mean of 3.5 procedures.
Conclusions: Overall
prosthetic survival (92.8%) has proven to be greater than most surgeons
anticipated in the early days of limb-salvage surgery. At an average
follow-up of 7 years, 67% (36/54) patients who required reoperation
were able to retain their prostheses. All patients with soft tissue
complications were salvaged with an average of 3 procedures, while
45% (5/11) of patients with deep infections were salvaged. Prosthetic
failure due to mechanical complications diminished significantly
from 64% (7/11) to 36% (4/11) with introduction in 1988 of modular
prostheses. Meticulous attention to technique and aggressive management
of soft-tissue complications leads to excellent prosthetic survival.
| Anatomic
location vs. Prosthetic Typs: |
|
|
|
D.
Femur
|
P.
Tibia
|
P.
Humerus
|
P.
Femur
|
Scapula
|
T.
Femur
|
Other
|
Total
|
|
Custom
|
19
|
9
|
6
|
9
|
11
|
9
|
4
|
78
|
|
Modular
|
74
|
31
|
32
|
24
|
0
|
7
|
5
|
173
|
|
Expandable
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
11
|
|
Total
|
93
|
40
|
38
|
33
|
11
|
16
|
9
|
251
|
| Complication
Type |
n
|
Follow-up
(months)
|
Interval between first and second surgery
|
#
Surgeries
|
Prosthesis
failure
|
| mechanical
|
20
|
121.5
|
45.5
|
3.6
|
(7 custom)
|
soft
tissue
(superficial) |
10
|
35.1
|
1.0
|
3.0
|
0
|
soft
tissue
(deep) |
5
|
76.6
|
44.1
|
3.0
|
0
|
| infection |
11
|
79.3
|
14.2
|
4.6
|
6
|
| dislocation |
2
|
29.8
|
7.8
|
3.0
|
0
|
| other |
6
|
81.3
|
7.8
|
3.0
|
1
|
| Overall |
54
|
85.4
|
25.5
|
3.5
|
18
|
| %
(÷251) |
21.5%
|
|
|
|
|
.
|