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Connective Tissue Oncology Society

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2002 CTOS Annual Meeting Oral Presentations — Surgery

LOW COMPLICATION RATE WITH LIMB-SPARING RESECTION AND ENDOPROSTHETIC RECONSTRUCTION: SURVIVAL ANALYSIS OF 251 PATIENTS AND ANALYSIS OF 20-YEAR EXPERIENCE
[Abstract ID: 59]

Category: Surgery

Presentation: Oral

Authors: Felasfa M Wodajo1, Kristen Kellar-Graney1, James C Wittig1, Robert M Henshaw1, Martin M Malawer1

Author Institutions: 1Washington Cancer Institute, DC, United States

Presenter: Felasfa M Wodajo
felasfa@earthlinl.net

Correspondent: Felasfa M Wodajo
felasfa@earthlinl.net
Washington DC United States 20010
Ph: 202-877-3970
Fax: 202-877-8959


Objectives: In order to evaluate patterns of complications and prosthetic survival after endoprosthetic reconstruction for bone tumors, the authors reviewed all procedures performed over a 20-year period at a single institution.

Methods: Patients who underwent one or more procedures with a segmental endoprosthesis, except for saddle prostheses, are reported. Prosthetic failure is defined as removal of a cemented component. Kaplan-Meier survival analysis, interval to complication and the number of operations per patient are calculated.

Results: A total of 251 patients underwent surgery. Of these, 197 patients (78%) underwent only one surgery. The remaining 54 underwent a mean of 3.5 procedures.

Conclusions: Overall prosthetic survival (92.8%) has proven to be greater than most surgeons anticipated in the early days of limb-salvage surgery. At an average follow-up of 7 years, 67% (36/54) patients who required reoperation were able to retain their prostheses. All patients with soft tissue complications were salvaged with an average of 3 procedures, while 45% (5/11) of patients with deep infections were salvaged. Prosthetic failure due to mechanical complications diminished significantly from 64% (7/11) to 36% (4/11) with introduction in 1988 of modular prostheses. Meticulous attention to technique and aggressive management of soft-tissue complications leads to excellent prosthetic survival.

Anatomic location vs. Prosthetic Typs:

D. Femur

P. Tibia

P. Humerus

P. Femur

Scapula

T. Femur

Other

Total

Custom

19

9

6

9

11

9

4

78

Modular

74

31

32

24

0

7

5

173

Expandable

0

0

0

0

0

0

0

11

Total

93

40

38

33

11

16

9

251


Complication Type
n
Follow-up
(months)
Interval between first and second surgery
# Surgeries
Prosthesis failure
mechanical
20
121.5
45.5
3.6
(7 custom)
soft tissue
(superficial)
10
35.1
1.0
3.0
0
soft tissue
(deep)
5
76.6
44.1
3.0
0
infection
11
79.3
14.2
4.6
6
dislocation
2
29.8

7.8

3.0
0
other
6
81.3
7.8

3.0

1
Overall
54
85.4
25.5
3.5
18
% (÷251)
21.5%

.


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